March 1, 2024
Image credit: PLOS
03/25/2024
Research Article
The authors introduce PathIntegrate, a method for integrating multi-omics datasets based on pathways, designed to exploit knowledge of biological systems and thus provide interpretable models for such studies.
Image credit: Wieder et al
Current Issue March 2024
03/13/2024
Research Article
Little is known about how deep learning discriminates against the features of neural signals. In this study, the authors perform behavioral classification from calcium imaging data of the mouse cortex and investigate brain regions important for the classification.
Image credit: Aijoka, Nakai, Yamashita, and Takumi
03/29/2024
Research Article
This study goes beyond the effects of reward outcomes on learning processes, to ask to what extent can modeling of behavior in a reinforcement-learning task be complicated by other sources of variance in sequential action choices? What of the effects of action bias and action hysteresis determined by the history of actions chosen previously?
Image credit: Planet Volumes
03/15/2024
Research Article
Population structure can amplify the action of selection and accelerate rates of evolution, or reversely, suppress selection and slow evolution down. Here the authors use evolutionary graph theory to study how higher-order motifs in a population’s network of interaction and replacement can shape the velocity of evolution.
Image credit: Kuo & Karja
03/14/2024
Methods
Dr. Luis Pedro Coelho discusses best practices for ensuring the long-term operability and accessibility of tools developed in bioinformatics.
Image credit: Mohammad Rahmani
02/29/2024
Research Article
The authors present the methodology behind TimeTeller, a machine learning tool that analyzes the clock as a noisy multigene dynamical system and aims to estimate circadian clock function from a single transcriptome by modeling the multi-dimensional state of the clock.
Image credit: Kenny Eliason
01/19/2024
Research Article
Understanding the intricate mechanisms governing human walking will contribute to the engineering applications such as walking assistive devices.
Image credit: Thom Milkovic
01/26/2024
Research Article
The transformer architecture has demonstrated remarkable, seemingly cognitive-like abilities, including puzzle solving, computer programming, image generation and style transformations.
Image credit: Ian T Ellwood
01/18/2024
Research Article
Image credit: NASA
01/19/2024
Research Article
Understanding how species interact and how this affects the robustness of ecological communities to species loss is essential to anticipate the consequences of biodiversity losses and extinctions.
Image credit: Ivan Bandura
This Collection aims to increase the coverage of computational biology-related topics in Wikipedia by rewarding authors with a citable, PubMed-indexed static version of the living document on Wikipedia.
This series of perspective articles from computational biologists in a variety of countries, offers their personal viewpoint on the history, current status, and future of computational biology in their region.
This collection aims to provide practical tutorials and background information on important computational methods used to investigate key biological questions, as well as resources for training scientists at all stages of their careers.
The Benchmarking collection help readers decide between a number of methods which are developed to solve scientific problems.
Knowledge-guided analysis of "omics" data using the KnowEnG cloud platform
Test accuracy of polymerase chain reaction methods against conventional diagnostic techniques for Cutaneous Leishmaniasis (CL) in patients with clinical or epidemiological suspicion of CL: Systematic review and meta-analysis
Murine and related chapparvoviruses are nephro-tropic and produce novel accessory proteins in infected kidneys
Prevalence and genetic profiles of isoniazid resistance in tuberculosis patients: A multicountry analysis of cross-sectional data
Connect with Us