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at the beginning

Posted by marcos-antezana on 29 Dec 2008 at 00:04 GMT

too bad that these very interesting computer-based studies are not realistic in that they have things in the wrong order: in a red-queen-ish nature injuries are inflicted onto you by other mean things as they try to get you --not just suffered when say you hit a computer desk-- and therefore it's much more likely that development evolved as a side effect of the evolution of defenses against wound-causing attack by others and that the cell-to-cell contacts involved in “regeneration” were first evolved to allow the rejection of alien cells that caused wounds on then amorphous akin-cell aggregates which couldn’t have cared less about their “morphogenetic homeostasis”. the repertoire of mechanisms involved in the wound-containment reaction in very simple cell aggregates should rather be explored regarding its epiphenomenal co-optability for morphogenesis.

squids etc

marcos-antezana replied to marcos-antezana on 29 Dec 2008 at 18:54 GMT

[...] Although little is known about cephalopod blood cells, current evidence suggests that there is only one type, the macrophage-like hemocyte (Cowden and Curtis, 1981; Nyholm and McFall-Ngai, 1998). Like the hemocytes of other molluscs, these cells participate in immune responses by phagocytosing or encapsulating bacteria and other foreign particles (Cowden and Curtis, 1981; Ford, 1992; Beuerlein and Schipp, 1998; Malham and Runham, 1998; Nyholm and McFall-Ngai, 1998). Cephalopod hemocytes also participate in tissue morphogenesis, repairing damaged tissue by forming cellular clots, or secreting collagen to block epithelial barrier disruptions (Jullien, 1928; Cowden and Curtis, 1981; Polglase et al., 1983; Feral, 1988; Ford, 1992). Some evidence also suggests that they can induce tissue histolysis during inflammatory reactions (Jullien, 1927; Jacquemain et al., 1947; Cowden and Curtis, 1981; Feral, 1988).

from Responses of Host Hemocytes During the Initiation of the Squid-Vibrio Symbiosis
Tanya A. Koropatnick, Jennifer R. Kimbell and Margaret J. McFall-Ngai*

Pacific Biomedical Research Center, Kewalo Marine Laboratory, University of Hawaii

* To whom correspondence should be addressed, at Department of Medical Microbiology and Immunology, University of Wisconsin, 1300 University Avenue, Madison, WI 53706. E-mail: mjmcfallngai@wisc.edu