Discarding Functional Residues from the Substitution Table Improves Predictions of Active Sites within Three-Dimensional Structures

Open Access

Peer-reviewed

Research Article

Sungsam Gong,

Affiliation Biocomputing Group, Department of Biochemistry, University of Cambridge, Cambridge, United Kingdom
⨯
Tom L. Blundell

* E-mail: tom@cryst.bioc.cam.ac.uk

Affiliation Biocomputing Group, Department of Biochemistry, University of Cambridge, Cambridge, United Kingdom
⨯

Reader Comments

Mapping UniProt and PDB at Residue Level
http://ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1000179#article1.body1.sec3.sec2.p1

As an author of this paper, I would like to introduce SAMUL (http://mordred.bioc.cam.ac.uk/samul) which is a web-based database sever focusing on structural/functional annotations of proteins. The double-map method, mentioned in this section, has been implemented, hence mapping information between PDB and UniProt sequence is now provided.

Please visit the website below for more information:
http://mordred.bioc.cam.ac.uk/samul

No competing interests declared.

Protein interactions
Is the Subject Area "Protein interactions" applicable to this article?

Thanks for your feedback.
Amino acid substitution
Is the Subject Area "Amino acid substitution" applicable to this article?

Thanks for your feedback.
Protein structure comparison
Is the Subject Area "Protein structure comparison" applicable to this article?

Thanks for your feedback.
Protein structure
Is the Subject Area "Protein structure" applicable to this article?

Thanks for your feedback.
Sequence alignment
Is the Subject Area "Sequence alignment" applicable to this article?

Thanks for your feedback.
Multiple alignment calculation
Is the Subject Area "Multiple alignment calculation" applicable to this article?

Thanks for your feedback.
Enzyme structure
Is the Subject Area "Enzyme structure" applicable to this article?

Thanks for your feedback.
Protein structure prediction
Is the Subject Area "Protein structure prediction" applicable to this article?

Thanks for your feedback.