Use of Data-Biased Random Walks on Graphs for the Retrieval of Context-Specific Networks from Genomic Data

Open Access

Peer-reviewed

Research Article

Kakajan Komurov ,

* E-mail: kkomurov@mdanderson.org

Affiliation Department of Systems Biology, University of Texas M.D. Anderson Cancer Center, Houston, Texas, United States of America
⨯
Michael A. White,

Affiliation Department of Cell Biology, University of Texas Southwestern Medical Center, Dallas, Texas, United States of America
⨯
Prahlad T. Ram

Affiliation Department of Systems Biology, University of Texas M.D. Anderson Cancer Center, Houston, Texas, United States of America
⨯

Reader Comments

over-expressed gene
http://ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1000889#article1.body1.sec1.p1

excessive expression of a gene by producing too much of its effect or product now suspect that many, if not most, cancers arise through the overexpression …of key cellular regulatory genes

No competing interests declared.

Genetic networks
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Gene expression
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Random walk
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Cell cycle and cell division
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Genome analysis
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Genomics
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Apoptosis
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Microarrays
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