Revisiting Date and Party Hubs: Novel Approaches to Role Assignment in Protein Interaction Networks

Sumeet Agarwal; Charlotte M. Deane; Mason A. Porter; Nick S. Jones

doi:10.1371/journal.pcbi.1000817

Loading metrics

Open Access

Peer-reviewed

Research Article

Revisiting Date and Party Hubs: Novel Approaches to Role Assignment in Protein Interaction Networks

Sumeet Agarwal,

Affiliations Systems Biology Doctoral Training Centre, University of Oxford, Oxford, United Kingdom, Department of Physics, University of Oxford, Oxford, United Kingdom
⨯
Charlotte M. Deane,

Affiliations Department of Statistics, University of Oxford, Oxford, United Kingdom, Oxford Centre for Integrative Systems Biology, University of Oxford, Oxford, United Kingdom
⨯
Mason A. Porter,

Affiliations Oxford Centre for Industrial and Applied Mathematics, Mathematical Institute, University of Oxford, Oxford, United Kingdom, CABDyN Complexity Centre, University of Oxford, Oxford, United Kingdom
⨯
Nick S. Jones

* E-mail: Nick.Jones@physics.ox.ac.uk

Affiliations Department of Physics, University of Oxford, Oxford, United Kingdom, Oxford Centre for Integrative Systems Biology, University of Oxford, Oxford, United Kingdom, CABDyN Complexity Centre, University of Oxford, Oxford, United Kingdom
⨯

Revisiting Date and Party Hubs: Novel Approaches to Role Assignment in Protein Interaction Networks

Sumeet Agarwal,
Charlotte M. Deane,
Mason A. Porter,
Nick S. Jones

Published: June 17, 2010
https://doi.org/10.1371/journal.pcbi.1000817

Reader Comments

Post a new comment on this article

rate of false positives is too high

Posted by GiovanniMDallOlio on 18 Jun 2010 at 09:13 GMT

I always suspected that the rate of false positives in protein-protein interactions experiments and databases was too high to make complete studies on it. Interesting article.

No competing interests declared.

Subject Areas
?

For more information about PLOS Subject Areas, click here.
We want your feedback. Do these Subject Areas make sense for this article? Click the target next to the incorrect Subject Area and let us know. Thanks for your help!

Protein interaction networks
Is the Subject Area "Protein interaction networks" applicable to this article?

Thanks for your feedback.
Protein interactions
Is the Subject Area "Protein interactions" applicable to this article?

Thanks for your feedback.
Interaction networks
Is the Subject Area "Interaction networks" applicable to this article?

Thanks for your feedback.
Yeast
Is the Subject Area "Yeast" applicable to this article?

Thanks for your feedback.
Centrality
Is the Subject Area "Centrality" applicable to this article?

Thanks for your feedback.
Saccharomyces cerevisiae
Is the Subject Area "Saccharomyces cerevisiae" applicable to this article?

Thanks for your feedback.
Community structure
Is the Subject Area "Community structure" applicable to this article?

Thanks for your feedback.
Microarrays
Is the Subject Area "Microarrays" applicable to this article?

Thanks for your feedback.

Revisiting Date and Party Hubs: Novel Approaches to Role Assignment in Protein Interaction Networks

Revisiting Date and Party Hubs: Novel Approaches to Role Assignment in Protein Interaction Networks

Reader Comments

Post Your Discussion Comment

Why should this posting be reviewed?

Thank You!

rate of false positives is too high

Posted by GiovanniMDallOlio on 18 Jun 2010 at 09:13 GMT