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Research Article

Animal Cell Differentiation Patterns Suppress Somatic Evolution

  • John W Pepper mail,

    To whom correspondence should be addressed. E-mail: jpepper1@email.arizona.edu

    Affiliations: Department of Ecology and Evolutionary Biology, University of Arizona, Tucson, Arizona, United States of America, The Santa Fe Institute, Santa Fe, New Mexico, United States of America

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  • Kathleen Sprouffske,

    Affiliations: Genomics and Computational Biology Program, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America, Systems Biology Division, The Wistar Institute, Philadelphia, Pennsylvania, United States of America

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  • Carlo C Maley

    Affiliation: Systems Biology Division, The Wistar Institute, Philadelphia, Pennsylvania, United States of America

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  • Published: December 14, 2007
  • DOI: 10.1371/journal.pcbi.0030250

Reader Comments (1)

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Groundbreaking work

Posted by jpepper1 on 12 Mar 2008 at 18:06 GMT

The questions addressed here are of fundamental importance to both basic and applied biology (e.g., cancer biology).