Advertisement
Research Article

Harvesting Candidate Genes Responsible for Serious Adverse Drug Reactions from a Chemical-Protein Interactome

  • Lun Yang mail,

    lunyang@gmail.com (LY); helinhelin@gmail.com (LH)

    Affiliations: Bio-X Center, Key Laboratory for the Genetics of Developmental and Neuropsychiatric Disorders (Ministry of Education), Shanghai Jiao Tong University, Shanghai, China, Institute of Biomedical Sciences, Fudan University, Shanghai, China

    X
  • Jian Chen,

    Affiliation: Bio-X Center, Key Laboratory for the Genetics of Developmental and Neuropsychiatric Disorders (Ministry of Education), Shanghai Jiao Tong University, Shanghai, China

    X
  • Lin He mail

    lunyang@gmail.com (LY); helinhelin@gmail.com (LH)

    Affiliations: Bio-X Center, Key Laboratory for the Genetics of Developmental and Neuropsychiatric Disorders (Ministry of Education), Shanghai Jiao Tong University, Shanghai, China, Institute of Biomedical Sciences, Fudan University, Shanghai, China, Institute for Nutritional Sciences, Shanghai Institutes of Biological Sciences, Chinese Academy of Sciences, Shanghai, China

    X
  • Published: July 24, 2009
  • DOI: 10.1371/journal.pcbi.1000441

Reader Comments (1)

Post a new comment on this article

A good piece of work on the methodology and mechanism of the adverse drug reaction

Posted by Felico on 02 Sep 2009 at 22:59 GMT


This work provides a good insight into the mechanism of adverse drug reaction. The authors recovered some of the successful ADR stories, however, the experimental validations are still needed.

No competing interests declared.