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Research Article

Google Goes Cancer: Improving Outcome Prediction for Cancer Patients by Network-Based Ranking of Marker Genes

  • Christof Winter equal contributor mail,

    equal contributor Contributed equally to this work with: Christof Winter, Glen Kristiansen, Stephan Kersting

    winter@biotec.tu-dresden.de

    Affiliation: Department of Bioinformatics, Biotechnology Center, Technische Universität Dresden, Dresden, Germany

    X
  • Glen Kristiansen equal contributor,

    equal contributor Contributed equally to this work with: Christof Winter, Glen Kristiansen, Stephan Kersting

    Affiliation: Institute of Pathology, Universitätsspital Zürich, Zurich, Switzerland

    X
  • Stephan Kersting equal contributor,

    equal contributor Contributed equally to this work with: Christof Winter, Glen Kristiansen, Stephan Kersting

    Affiliation: Department of Visceral, Thoracic, and Vascular Surgery, University Hospital Carl Gustav Carus, Dresden, Germany

    X
  • Janine Roy,

    Affiliation: Department of Bioinformatics, Biotechnology Center, Technische Universität Dresden, Dresden, Germany

    X
  • Daniela Aust,

    Affiliation: Institute of Pathology, University Hospital Carl Gustav Carus, Dresden, Germany

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  • Thomas Knösel,

    Affiliation: Institute of Pathology, University of Jena, Jena, Germany

    X
  • Petra Rümmele,

    Affiliation: Institute of Pathology, University of Regensburg, Regensburg, Germany

    X
  • Beatrix Jahnke,

    Affiliation: Department of Visceral, Thoracic, and Vascular Surgery, University Hospital Carl Gustav Carus, Dresden, Germany

    X
  • Vera Hentrich,

    Affiliation: Department of Visceral, Thoracic, and Vascular Surgery, University Hospital Carl Gustav Carus, Dresden, Germany

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  • Felix Rückert,

    Affiliation: Department of Visceral, Thoracic, and Vascular Surgery, University Hospital Carl Gustav Carus, Dresden, Germany

    X
  • Marco Niedergethmann,

    Affiliation: Department of Surgery, University Hospital Mannheim, Mannheim, Germany

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  • Wilko Weichert,

    Affiliation: Department of Pathology, Charité, Berlin, Germany

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  • Marcus Bahra,

    Affiliation: Department of Surgery, Charité, Berlin, Germany

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  • Hans J. Schlitt,

    Affiliation: Department of Surgery, University Hospital Regensburg, Regensburg, Germany

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  • Utz Settmacher,

    Affiliation: Department of Surgery, University Hospital Jena, Jena, Germany

    X
  • Helmut Friess,

    Affiliation: Department of Surgery, Technische Universität München, München, Germany

    X
  • Markus Büchler,

    Affiliation: Department of Surgery, University of Heidelberg, Heidelberg, Germany

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  • Hans-Detlev Saeger,

    Affiliation: Department of Visceral, Thoracic, and Vascular Surgery, University Hospital Carl Gustav Carus, Dresden, Germany

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  • Michael Schroeder ,

    Affiliation: Department of Bioinformatics, Biotechnology Center, Technische Universität Dresden, Dresden, Germany

    These authors are joint senior authors on this work.

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  • Christian Pilarsky ,

    Affiliation: Department of Visceral, Thoracic, and Vascular Surgery, University Hospital Carl Gustav Carus, Dresden, Germany

    These authors are joint senior authors on this work.

    X
  • Robert Grützmann

    Affiliation: Department of Visceral, Thoracic, and Vascular Surgery, University Hospital Carl Gustav Carus, Dresden, Germany

    These authors are joint senior authors on this work.

    X
  • Published: May 17, 2012
  • DOI: 10.1371/journal.pcbi.1002511

Reader Comments (3)

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Press Coverage of 'Google Goes Cancer...'

Posted by PLoS_CompBiol on 24 May 2012 at 11:20 GMT

The following article represents some of the media coverage that has occurred for this paper:

1) Publication: Smart Planet

Title: Cancer? Google it

URL: http://www.smartplanet.co...

2) Publication: Biotechniques

Title: Google Goes Cancer

URL: http://www.biotechniques....

3) Publication: Science Illustrated

Title: Cancer can be tracked with Google

URL: http://scienceillustrated...


If you see any additional coverage of this paper in the press or blogosphere, please reply to this thread and add the link to the article.


No competing interests declared.

RE: Press Coverage of 'Google Goes Cancer...'

Christof replied to PLoS_CompBiol on 24 May 2012 at 14:42 GMT

4) Publication: Txchnologist
Googling Cancer: Search Algorithms Can Scan Disease for Patient Risk
http://www.txchnologist.c...

5) Publication: Spanish Scientific News Agency (SINC)
Los algoritmos de Google y Facebook se aplican en la investigación contra el cáncer
http://www.agenciasinc.es...

6) Publication: Slashdot
Researchers Use Google's Search Algorithms To Fight Cancer
http://science.slashdot.o...

7) Publication: Stanford Scope
Google-like algorithm may reveal better biomarkers for cancer
http://scopeblog.stanford...

8) Publication: The Munich Times
German researchers use google-based search approach for cancer treatment
http://www.themunichtimes...

9) Publication: Scientific Sense
The algorithm hype
http://www.scientificsens...

10) Publication: Ars Technica
Can PageRank-like approach aid fight against cancer?
http://arstechnica.com/sc...

No competing interests declared.