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Research Article

SnIPRE: Selection Inference Using a Poisson Random Effects Model

  • Kirsten E. Eilertson mail,

    cdbustam@stanford.edu

    Affiliation: Bioinformatics Core, J David Gladstone Institutes, San Francisco, California, United States of America

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  • James G. Booth,

    Affiliation: Department of Biological Statistics and Computational Biology, Cornell University, Ithaca, New York, United States of America

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  • Carlos D. Bustamante

    Affiliation: Department of Genetics, Stanford University, Stanford, California, United States of America

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  • Published: December 06, 2012
  • DOI: 10.1371/journal.pcbi.1002806

Reader Comments (1)

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A very valuable addition to population genomics tools

Posted by clementkent on 19 Dec 2012 at 23:41 GMT

This article and method deserves careful study by everyone working in population genomics. It represents a real advance.

One quibble: I am not clear what happens with genes where there are 0 cells in the M-K table. Are these genes not used or is there a substitute value such as .5 used?zeros?

No competing interests declared.