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Research Article

Prediction of Drug-Target Interactions and Drug Repositioning via Network-Based Inference

  • Feixiong Cheng equal contributor,

    equal contributor Contributed equally to this work with: Feixiong Cheng, Chuang Liu

    Affiliation: Shanghai Key Laboratory of New Drug Design, School of Pharmacy, East China University of Science and Technology, Shanghai, China

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  • Chuang Liu equal contributor,

    equal contributor Contributed equally to this work with: Feixiong Cheng, Chuang Liu

    Affiliation: School of Business, East China University of Science and Technology, Shanghai, China

    X
  • Jing Jiang,

    Affiliation: Shanghai Key Laboratory of New Drug Design, School of Pharmacy, East China University of Science and Technology, Shanghai, China

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  • Weiqiang Lu,

    Affiliation: Shanghai Key Laboratory of New Drug Design, School of Pharmacy, East China University of Science and Technology, Shanghai, China

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  • Weihua Li,

    Affiliation: Shanghai Key Laboratory of New Drug Design, School of Pharmacy, East China University of Science and Technology, Shanghai, China

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  • Guixia Liu,

    Affiliation: Shanghai Key Laboratory of New Drug Design, School of Pharmacy, East China University of Science and Technology, Shanghai, China

    X
  • Weixing Zhou mail,

    wxzhou@ecust.edu.cn (WZ); huangjin@ecust.edu.cn (JH); ytang234@ecust.edu.cn (YT)

    Affiliation: School of Business, East China University of Science and Technology, Shanghai, China

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  • Jin Huang mail,

    wxzhou@ecust.edu.cn (WZ); huangjin@ecust.edu.cn (JH); ytang234@ecust.edu.cn (YT)

    Affiliation: Shanghai Key Laboratory of New Drug Design, School of Pharmacy, East China University of Science and Technology, Shanghai, China

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  • Yun Tang mail

    wxzhou@ecust.edu.cn (WZ); huangjin@ecust.edu.cn (JH); ytang234@ecust.edu.cn (YT)

    Affiliation: Shanghai Key Laboratory of New Drug Design, School of Pharmacy, East China University of Science and Technology, Shanghai, China

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  • Published: May 10, 2012
  • DOI: 10.1371/journal.pcbi.1002503

Reader Comments (1)

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Paper Citation

Posted by abhik1368 on 02 Feb 2013 at 04:57 GMT

I think the author should have cited this paper http://www.pnas.org/conte...

The algorithms looks similar and basically the method is not new actually the algorithm is eventually applied in other domain of interest.

No competing interests declared.

RE: Paper Citation

ytang234 replied to abhik1368 on 27 Feb 2013 at 23:16 GMT

In our paper, the item-based collaborative filtering and user-based collaborative filtering algorithms have cited the references 20 (Sarwar et al., In Proceedings of the World Wide Web Conference (WWWC10), 2001, 285–295.) and 21 (Herlocker et al., ACM T Inform Syst., 2004, 22: 5-53.). The network-based inference (NBI) method has cited the ref 19 (Zhou et al. New J Phys. 2007, 11: 123008.). Today, the collaborative filtering and NBI algorithms have been used and published by many papers in the area of economic and social complex network, but not in drug discovery field. We can not cite every related paper. So we did not cite the similar paper (Hidalgo et al., PNAS, 2009, 106: 10570-10575).

No competing interests declared.