A Model of Cardiovascular Disease Giving a Plausible Mechanism for the Effect of Fractionated Low-Dose Ionizing Radiation Exposure

Mark P. Little; Anna Gola; Ioanna Tzoulaki

doi:10.1371/journal.pcbi.1000539

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Peer-reviewed

Research Article

A Model of Cardiovascular Disease Giving a Plausible Mechanism for the Effect of Fractionated Low-Dose Ionizing Radiation Exposure

Mark P. Little ,

* E-mail: mark.little@imperial.ac.uk

Affiliation Department of Epidemiology and Public Health, Faculty of Medicine, Imperial College London, London, United Kingdom
⨯
Anna Gola,

Affiliation Department of Epidemiology and Public Health, Faculty of Medicine, Imperial College London, London, United Kingdom
⨯
Ioanna Tzoulaki

Affiliation Department of Epidemiology and Public Health, Faculty of Medicine, Imperial College London, London, United Kingdom
⨯

A Model of Cardiovascular Disease Giving a Plausible Mechanism for the Effect of Fractionated Low-Dose Ionizing Radiation Exposure

Mark P. Little,
Anna Gola,
Ioanna Tzoulaki

Published: October 23, 2009
https://doi.org/10.1371/journal.pcbi.1000539

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Monocyte and T-lymphocyte trans-endothelial migration in relation to cardiovascular disease: some alternative boundary conditions in a model recently proposed by Little et al. (PLoS Comput Biol 2009 5(10) e1000539)

Posted by mlittle on 28 Feb 2010 at 17:50 GMT

In the Cornell arXiv (see http://arxiv.org/) document 1003.0199 we consider slight modifications to the monocyte and T-lymphocyte boundary conditions of Little et al. (PLoS Comput Biol 2009 5(10) e1000539) (equations (17) and (18) in the main text). We derive parameter estimates for the new equations and correct some typos in the older parameter estimates.

Because the earlier paper generally assumed no-flux boundary conditions in equilibrium, no changes to the results and conclusions of the paper of Little et al. (PLoS Comput Biol 2009 5(10) e1000539) are implied.

No competing interests declared.

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A Model of Cardiovascular Disease Giving a Plausible Mechanism for the Effect of Fractionated Low-Dose Ionizing Radiation Exposure

A Model of Cardiovascular Disease Giving a Plausible Mechanism for the Effect of Fractionated Low-Dose Ionizing Radiation Exposure

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Monocyte and T-lymphocyte trans-endothelial migration in relation to cardiovascular disease: some alternative boundary conditions in a model recently proposed by Little et al. (PLoS Comput Biol 2009 5(10) e1000539)

Posted by mlittle on 28 Feb 2010 at 17:50 GMT