Competition for Antigen between Th1 and Th2 Responses Determines the Timing of the Immune Response Switch during Mycobaterium avium Subspecies paratuberulosis Infection in Ruminants

Gesham Magombedze; Shigetoshi Eda; Vitaly V. Ganusov

doi:10.1371/journal.pcbi.1003414

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Open Access

Peer-reviewed

Research Article

Competition for Antigen between Th1 and Th2 Responses Determines the Timing of the Immune Response Switch during Mycobaterium avium Subspecies paratuberulosis Infection in Ruminants

Gesham Magombedze ,

* E-mail: gmagombedze@nimbios.org; gmagombedze@gmail.com

Affiliation National Institute for Mathematical and Biological Synthesis, University of Tennessee, Knoxville, Tennesse, United States of America
⨯
Shigetoshi Eda,

Affiliation Department of Forestry, Wildlife, and Fisheries, University of Tennessee, Knoxville, Tennesse, United States of America
⨯
Vitaly V. Ganusov

Affiliations National Institute for Mathematical and Biological Synthesis, University of Tennessee, Knoxville, Tennesse, United States of America, Department of Microbiology, University of Tennessee, Knoxville, Tennesse, United States of America, Department of Mathematics, University of Tennessee, Knoxville, Tennesse, United States of America
⨯

Competition for Antigen between Th1 and Th2 Responses Determines the Timing of the Immune Response Switch during Mycobaterium avium Subspecies paratuberulosis Infection in Ruminants

Gesham Magombedze,
Shigetoshi Eda,
Vitaly V. Ganusov

Published: January 9, 2014
https://doi.org/10.1371/journal.pcbi.1003414

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antibiotics?

Posted by drchristine on 05 May 2014 at 02:45 GMT

Just curious if these animals in the study had received antibiotics.. could that affect the switch from Th1 to Th2 at all?

Purely curiosity here.

Thanks!

No competing interests declared.

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Competition for Antigen between Th1 and Th2 Responses Determines the Timing of the Immune Response Switch during Mycobaterium avium Subspecies paratuberulosis Infection in Ruminants

Competition for Antigen between Th1 and Th2 Responses Determines the Timing of the Immune Response Switch during Mycobaterium avium Subspecies paratuberulosis Infection in Ruminants

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antibiotics?

Posted by drchristine on 05 May 2014 at 02:45 GMT