Use of Data-Biased Random Walks on Graphs for the Retrieval of Context-Specific Networks from Genomic Data

Open Access

Peer-reviewed

Research Article

Kakajan Komurov ,

* E-mail: kkomurov@mdanderson.org

Affiliation Department of Systems Biology, University of Texas M.D. Anderson Cancer Center, Houston, Texas, United States of America
⨯
Michael A. White,

Affiliation Department of Cell Biology, University of Texas Southwestern Medical Center, Dallas, Texas, United States of America
⨯
Prahlad T. Ram

Affiliation Department of Systems Biology, University of Texas M.D. Anderson Cancer Center, Houston, Texas, United States of America
⨯

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p53
http://ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1000889#article1.front1.article-meta1.abstract1.p1

p53 (also known as protein 53 or tumor protein 53), is a tumor suppressor protein that in humans is encoded by the TP53 gene.[1][2][3] p53 is important in multicellular organisms, where it regulates the cell cycle and, thus, functions as a tumor suppressor that is involved in preventing cancer

No competing interests declared.

Genetic networks
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Gene expression
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Random walk
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Cell cycle and cell division
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Genome analysis
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Genomics
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Apoptosis
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Microarrays
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