About the Authors

Jie Song

Affiliations Verna and Marrs McLean Department of Biochemistry and Molecular Biology, Baylor College of Medicine, Houston, Texas, United States of America , Verna and Marrs McLean Department of Biochemistry and Molecular Biology, Baylor College of Medicine, Houston, Texas, United States of America

Qikai Xu

Affiliations Department of Human Genetics, Baylor College of Medicine, Houston, Texas, United States of America , Graduate Program in Structural and Computational Biology and Molecular Biophysics, Baylor College of Medicine, Houston, Texas, United States of America , Verna and Marrs McLean Department of Biochemistry and Molecular Biology, Baylor College of Medicine, Houston, Texas, United States of America

Rolf Olsen

Affiliations Section of Cell and Developmental Biology, Division of Biology, University of California San Diego, La Jolla, California, United States of America , Verna and Marrs McLean Department of Biochemistry and Molecular Biology, Baylor College of Medicine, Houston, Texas, United States of America

William F Loomis

Affiliations Section of Cell and Developmental Biology, Division of Biology, University of California San Diego, La Jolla, California, United States of America , Verna and Marrs McLean Department of Biochemistry and Molecular Biology, Baylor College of Medicine, Houston, Texas, United States of America

Gad Shaulsky

Affiliations Department of Human Genetics, Baylor College of Medicine, Houston, Texas, United States of America , Graduate Program in Structural and Computational Biology and Molecular Biophysics, Baylor College of Medicine, Houston, Texas, United States of America , Verna and Marrs McLean Department of Biochemistry and Molecular Biology, Baylor College of Medicine, Houston, Texas, United States of America

Adam Kuspa

Affiliations Verna and Marrs McLean Department of Biochemistry and Molecular Biology, Baylor College of Medicine, Houston, Texas, United States of America , Department of Human Genetics, Baylor College of Medicine, Houston, Texas, United States of America , Verna and Marrs McLean Department of Biochemistry and Molecular Biology, Baylor College of Medicine, Houston, Texas, United States of America

Richard Sucgang

To whom correspondence should be addressed. E-mail: rsucgang@bcm.tmc.edu

Affiliations Verna and Marrs McLean Department of Biochemistry and Molecular Biology, Baylor College of Medicine, Houston, Texas, United States of America , Verna and Marrs McLean Department of Biochemistry and Molecular Biology, Baylor College of Medicine, Houston, Texas, United States of America

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

RO, AK, and RS conceived and designed the experiments. JS, RO, and RS performed the experiments. JS, QX, RO, WFL, and RS analyzed the data. JS, QX, RO, WFL, and GS contributed reagents/materials/analysis tools. GS participated in intellectual discussion and supervised experiments. RS supervised the work. WFL, AK, and RS wrote the paper.