About the Authors
- Dmitry Korkin
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Affiliations Department of Biopharmaceutical Sciences, University of California San Francisco, San Francisco, California, United States of America , Department of Pharmaceutical Chemistry, University of California San Francisco, San Francisco, California, United States of America , California Institute for Quantitative Biomedical Research, University of California San Francisco, San Francisco, California, United States of America
- Fred P Davis
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Affiliations Department of Biopharmaceutical Sciences, University of California San Francisco, San Francisco, California, United States of America , Department of Pharmaceutical Chemistry, University of California San Francisco, San Francisco, California, United States of America , California Institute for Quantitative Biomedical Research, University of California San Francisco, San Francisco, California, United States of America
- Frank Alber
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Affiliations Department of Biopharmaceutical Sciences, University of California San Francisco, San Francisco, California, United States of America , Department of Pharmaceutical Chemistry, University of California San Francisco, San Francisco, California, United States of America , California Institute for Quantitative Biomedical Research, University of California San Francisco, San Francisco, California, United States of America
- Tinh Luong
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Affiliation Division of Biology, California Institute of Technology, Pasadena, California, United States of America
- Min-Yi Shen
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Affiliations Department of Biopharmaceutical Sciences, University of California San Francisco, San Francisco, California, United States of America , Department of Pharmaceutical Chemistry, University of California San Francisco, San Francisco, California, United States of America , California Institute for Quantitative Biomedical Research, University of California San Francisco, San Francisco, California, United States of America
- Vladan Lucic
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Affiliation Department of Structural Biology, Max Planck Institute of Biochemistry, Martinsried, Germany
- Mary B Kennedy
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Affiliation Division of Biology, California Institute of Technology, Pasadena, California, United States of America
- Andrej Sali
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*To whom correspondence should be addressed. E-mail: sali@salilab.org
Affiliations Department of Biopharmaceutical Sciences, University of California San Francisco, San Francisco, California, United States of America , Department of Pharmaceutical Chemistry, University of California San Francisco, San Francisco, California, United States of America , California Institute for Quantitative Biomedical Research, University of California San Francisco, San Francisco, California, United States of America
Competing Interests
The authors have declared that no competing interests exist.
Author Contributions
DK and AS conceived and designed the experiments. DK and TL performed the experiments. DK, FPD, FA, MBK, and AS analyzed the data. DK, FA, TL, MYS, VL, and MBK contributed reagents/materials/analysis tools. DK, FPD, FA, TL, MBK, and AS wrote the paper.