About the Authors

Sebastian Will

Affiliation Bioinformatics Group, Institute of Computer Science, University of Freiburg, Freiburg, Germany

Kristin Reiche

Affiliation Bioinformatics Group, Department of Computer Science, University of Leipzig, Leipzig, Germany

Ivo L Hofacker

Affiliation Department of Theoretical Chemistry, University of Vienna, Vienna, Austria

Peter F Stadler

Affiliation Bioinformatics Group, Department of Computer Science, University of Leipzig, Leipzig, Germany

Rolf Backofen

To whom correspondence should be addressed. E-mail: backofen@informatik.uni-freiburg.de

Affiliation Bioinformatics Group, Institute of Computer Science, University of Freiburg, Freiburg, Germany

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

All authors conceived and designed the experiments and contributed to writing the paper. SW developed and implemented the algorithm and performed the experiments. KR analyzed the data and contributed analysis tools.