About the Authors
- Katrin Hübner
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* E-mail: katrin.huebner@bioquant.uni-heidelberg.de
Current address: BIOQUANT, Modeling Biological Processes, Institute of Zoology, University of Heidelberg, Heidelberg, Germany.
Affiliations Computational Systems Biochemistry, Institute of Biochemistry, Charité-Universitätsmedizin Berlin, Germany, Bioinformatics Group, Max Delbrück Center for Molecular Medicine Berlin-Buch, Germany
- Thomas Schwager
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Affiliation Computational Systems Biochemistry, Institute of Biochemistry, Charité-Universitätsmedizin Berlin, Germany
- Karl Winkler
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Affiliation Department of Clinical Chemistry, University Hospital Freiburg, Germany
- Jens-Georg Reich
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Affiliation Bioinformatics Group, Max Delbrück Center for Molecular Medicine Berlin-Buch, Germany
- Hermann-Georg Holzhütter
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Affiliation Computational Systems Biochemistry, Institute of Biochemistry, Charité-Universitätsmedizin Berlin, Germany
Competing Interests
The authors have declared that no competing interests exist.
Author Contributions
Performed the experiments: KW. Analyzed the data: KH. Contributed reagents/materials/analysis tools: TS KW. Wrote the paper: KH TS HH. Data-mined the literature; contributed to the model design; performed model building, implementations, and simulations; conceived and performed in-silico experiments and analyses: KH. Provided stochastic modeling experience and model implementations and contributed to the model design, simulations and analyses: TS. Provided experimental work and clinical experience in lipid diagnostics: KW. Provided mathematical modeling experience and lipoprotein metabolism knowledge: JR. Contributed to the model design and provided mathematical modeling experience, model implementation, and simulation: HH.