About the Authors

Frank J. Bruggeman

frank.bruggeman@sysbio.nl

Affiliations Regulatory Networks Group, Netherlands Institute for Systems Biology, Amsterdam, The Netherlands, Life Sciences, Centre for Mathematics and Computer Science (CWI), Amsterdam, The Netherlands, Integrative Bioinformatics, VU University, Amsterdam, The Netherlands

Nils Blüthgen

Affiliation Institute of Pathology and Institute of Theoretical Biology, Charité Universitätsmedizin Berlin, Berlin, Germany

Hans V. Westerhoff

Affiliations Manchester Centre for Integrative Systems Biology, University of Manchester, Manchester, United Kingdom, Molecular Cell Physiology, Netherlands Institute for Systems Biology, VU University, Amsterdam, The Netherlands

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: FJB NB. Wrote the paper: FJB NB HVW.