About the Authors

Jun Zhu

Contributed equally to this work with: Jun Zhu, Yanqing Chen

junzhu_99@yahoo.com (JZ); eric.schadt@gmail.com (EES)

Current address: Sage Bionetworks, Seattle, Washington, United States of America

Affiliation Department of Genetics, Rosetta Inpharmatics, LLC, a wholly owned subsidiary of Merck & Co., Inc., Seattle, Washington, United States of America

Yanqing Chen

Contributed equally to this work with: Jun Zhu, Yanqing Chen

Current address: The Neurosciences Institute, San Diego, California, United States of America

Affiliation Department of Genetics, Rosetta Inpharmatics, LLC, a wholly owned subsidiary of Merck & Co., Inc., Seattle, Washington, United States of America

Amy S. Leonardson

Current address: Pathway Genomics, San Diego, California, United States of America

Affiliation Department of Genetics, Rosetta Inpharmatics, LLC, a wholly owned subsidiary of Merck & Co., Inc., Seattle, Washington, United States of America

Kai Wang

Current address: Pfizer Inc., San Diego, California, United States of America

Affiliation Department of Genetics, Rosetta Inpharmatics, LLC, a wholly owned subsidiary of Merck & Co., Inc., Seattle, Washington, United States of America

John R. Lamb

Current address: Pfizer Inc., San Diego, California, United States of America

Affiliation Department of Genetics, Rosetta Inpharmatics, LLC, a wholly owned subsidiary of Merck & Co., Inc., Seattle, Washington, United States of America

Valur Emilsson

Affiliation Molecular Profiling and Research Informatics Department, Merck Research Laboratories, Rahway, New Jersey, United States of America

Eric E. Schadt

junzhu_99@yahoo.com (JZ); eric.schadt@gmail.com (EES)

Current address: Pacific Biosciences, Menlo Park, California, United States of America

Affiliation Department of Genetics, Rosetta Inpharmatics, LLC, a wholly owned subsidiary of Merck & Co., Inc., Seattle, Washington, United States of America

Competing Interests

JZ, YC, ASL, KW, JRL, VE and EES work for Merck & Co. Inc., and own Merck's stocks.

Author Contributions

Conceived and designed the experiments: JZ YC EES. Analyzed the data: JZ YC. Contributed reagents/materials/analysis tools: JZ YC ASL KW JRL VE. Wrote the paper: JZ YC VE EES.