Optimality of Mutation and Selection in Germinal Centers

Open Access

Peer-reviewed

Research Article

Jingshan Zhang,

Affiliation Department of Chemistry and Chemical Biology, Harvard University, Cambridge, Massachusetts, United States of America
⨯
Eugene I. Shakhnovich

* E-mail: eugene@belok.harvard.edu

Affiliation Department of Chemistry and Chemical Biology, Harvard University, Cambridge, Massachusetts, United States of America
⨯

About the Authors

Jingshan Zhang

Affiliation Department of Chemistry and Chemical Biology, Harvard University, Cambridge, Massachusetts, United States of America

Eugene I. Shakhnovich

* E-mail: eugene@belok.harvard.edu

Affiliation Department of Chemistry and Chemical Biology, Harvard University, Cambridge, Massachusetts, United States of America

The authors have declared that no competing interests exist.

Conceived and designed the experiments: EIS. Performed the experiments: JZ EIS. Analyzed the data: JZ EIS. Wrote the paper: JZ EIS.

B cells
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Point mutation
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Mutation databases
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Cell binding
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Population size
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Cell migration
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Spleen
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Population dynamics
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