Gene Expression Network Reconstruction by Convex Feature Selection when Incorporating Genetic Perturbations

Benjamin A. Logsdon; Jason Mezey

doi:10.1371/journal.pcbi.1001014

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Open Access

Peer-reviewed

Research Article

Gene Expression Network Reconstruction by Convex Feature Selection when Incorporating Genetic Perturbations

Benjamin A. Logsdon,

Affiliation Department of Biological Statistics and Computational Biology, Cornell University, Ithaca, New York, United States of America
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Jason Mezey

* E-mail: jgm45@cornell.edu

Affiliations Department of Biological Statistics and Computational Biology, Cornell University, Ithaca, New York, United States of America, Department of Genetic Medicine, Weill Cornell Medical College, New York, New York, United States of America
⨯

Gene Expression Network Reconstruction by Convex Feature Selection when Incorporating Genetic Perturbations

Benjamin A. Logsdon,
Jason Mezey

Published: December 2, 2010
https://doi.org/10.1371/journal.pcbi.1001014

About the Authors

Benjamin A. Logsdon

Affiliation Department of Biological Statistics and Computational Biology, Cornell University, Ithaca, New York, United States of America

Jason Mezey

* E-mail: jgm45@cornell.edu

Affiliations Department of Biological Statistics and Computational Biology, Cornell University, Ithaca, New York, United States of America, Department of Genetic Medicine, Weill Cornell Medical College, New York, New York, United States of America

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: BAL JM. Performed the experiments: BAL. Analyzed the data: BAL. Wrote the paper: BAL JM. Derived theorem proofs: BAL.

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Gene expression
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Algorithms
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Genetic networks
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Graphs
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Gene regulation
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Directed acyclic graphs
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Phenotypes
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Genetics
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