About the Authors

Abdullah Hamadeh

Affiliations Department of Engineering Science, University of Oxford, Oxford, United Kingdom, Oxford Centre for Integrative Systems Biology, Department of Biochemistry, Oxford, United Kingdom

Mark A. J. Roberts

Affiliations Department of Engineering Science, University of Oxford, Oxford, United Kingdom, Oxford Centre for Integrative Systems Biology, Department of Biochemistry, Oxford, United Kingdom, Department of Biochemistry, University of Oxford, Oxford, United Kingdom

Elias August

Affiliations Department of Engineering Science, University of Oxford, Oxford, United Kingdom, Oxford Centre for Integrative Systems Biology, Department of Biochemistry, Oxford, United Kingdom

Patrick E. McSharry

Affiliations Oxford Centre for Integrative Systems Biology, Department of Biochemistry, Oxford, United Kingdom, Mathematical Institute, University of Oxford, Oxford, United Kingdom

Philip K. Maini

Affiliations Oxford Centre for Integrative Systems Biology, Department of Biochemistry, Oxford, United Kingdom, Centre for Mathematical Biology, Mathematical Institute, University of Oxford, Oxford, United Kingdom

Judith P. Armitage

Affiliations Oxford Centre for Integrative Systems Biology, Department of Biochemistry, Oxford, United Kingdom, Department of Biochemistry, University of Oxford, Oxford, United Kingdom

Antonis Papachristodoulou

antonis@eng.ox.ac.uk

Affiliations Department of Engineering Science, University of Oxford, Oxford, United Kingdom, Oxford Centre for Integrative Systems Biology, Department of Biochemistry, Oxford, United Kingdom

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: AH MAJR EA PKM JPA AP. Performed the experiments: AH MAJR EA. Analyzed the data: AH MAJR EA AP. Contributed reagents/materials/analysis tools: AH MAJR EA PEM JPA. Wrote the paper: AH MAJR EA PKM JPA AP.