Integrating Flux Balance Analysis into Kinetic Models to Decipher the Dynamic Metabolism of Shewanella oneidensis MR-1

Xueyang Feng; You Xu; Yixin Chen; Yinjie J. Tang

doi:10.1371/journal.pcbi.1002376

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Open Access

Peer-reviewed

Research Article

Integrating Flux Balance Analysis into Kinetic Models to Decipher the Dynamic Metabolism of Shewanella oneidensis MR-1

Xueyang Feng,

Affiliation Department of Energy, Environmental and Chemical Engineering, Washington University, St. Louis, Missouri, United States of America
⨯
You Xu,

Affiliation Department of Computer Science and Engineering, Washington University, St. Louis, Missouri, United States of America
⨯
Yixin Chen,

Affiliation Department of Computer Science and Engineering, Washington University, St. Louis, Missouri, United States of America
⨯
Yinjie J. Tang

* E-mail: yinjie.tang@seas.wustl.edu

Affiliation Department of Energy, Environmental and Chemical Engineering, Washington University, St. Louis, Missouri, United States of America
⨯

Integrating Flux Balance Analysis into Kinetic Models to Decipher the Dynamic Metabolism of Shewanella oneidensis MR-1

Xueyang Feng,
You Xu,
Yixin Chen,
Yinjie J. Tang

Published: February 2, 2012
https://doi.org/10.1371/journal.pcbi.1002376

About the Authors

Xueyang Feng

Affiliation Department of Energy, Environmental and Chemical Engineering, Washington University, St. Louis, Missouri, United States of America

You Xu

Affiliation Department of Computer Science and Engineering, Washington University, St. Louis, Missouri, United States of America

Yixin Chen

Affiliation Department of Computer Science and Engineering, Washington University, St. Louis, Missouri, United States of America

Yinjie J. Tang

* E-mail: yinjie.tang@seas.wustl.edu

Affiliation Department of Energy, Environmental and Chemical Engineering, Washington University, St. Louis, Missouri, United States of America

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: XF YJT. Performed the experiments: XF YX. Analyzed the data: XF YX YJT. Contributed reagents/materials/analysis tools: XF YX YC YJT. Wrote the paper: XF YJT.

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Pyruvate
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Protein metabolism
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Cell metabolism
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Metabolic labeling
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Optimization
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Body weight
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