About the Authors

Katja Rateitschak

katja.rateitschak@uni-rostock.de

Affiliation Department of Systems Biology and Bioinformatics, University of Rostock, Rostock, Germany

Felix Winter

Affiliation Department of Systems Biology and Bioinformatics, University of Rostock, Rostock, Germany

Falko Lange

Affiliations Department of Systems Biology and Bioinformatics, University of Rostock, Rostock, Germany, Department of Medicine II, Division of Gastroenterology, University Medicine Rostock, Rostock, Germany

Robert Jaster

Affiliation Department of Medicine II, Division of Gastroenterology, University Medicine Rostock, Rostock, Germany

Olaf Wolkenhauer

Affiliations Department of Systems Biology and Bioinformatics, University of Rostock, Rostock, Germany, Stellenbosch Institute for Advanced Study (STIAS), Wallenberg Research Center at Stellenbosch University, Stellenbosch, South Africa

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived the study and performed most of the numerical computations: KR. Coded and calculated the amount of overfitting of both models: FW. Performed the complementary experiments: FL. Participated in the interpretation of the results: KR FW FL RJ OW. Wrote the first version of the manuscript: KR. Subsequently revised the manuscript: KR FW FL RJ OW. Read and approved the final manuscript: KR FW FL RJ OW.