About the Authors

Rasmus Agren

Affiliation Department of Chemical and Biological Engineering, Chalmers University of Technology, Gothenburg, Sweden

Liming Liu

Affiliation Department of Chemical and Biological Engineering, Chalmers University of Technology, Gothenburg, Sweden

Saeed Shoaie

Affiliation Department of Chemical and Biological Engineering, Chalmers University of Technology, Gothenburg, Sweden

Wanwipa Vongsangnak

Affiliation Center for Systems Biology, Soochow University, Suzhou, China

Intawat Nookaew

Affiliation Department of Chemical and Biological Engineering, Chalmers University of Technology, Gothenburg, Sweden

Jens Nielsen

nielsenj@chalmers.se

Affiliation Department of Chemical and Biological Engineering, Chalmers University of Technology, Gothenburg, Sweden

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Performed the reconstruction: RA LL. Bioinformatics analyses: WV IN. Developed the sub-cellular localization algorithm: RA SS. Wrote the software and performed the simulations: RA. Supervised the work: IN JN. Conceived and designed the experiments: RA JN. Performed the experiments: RA LL SS. Analyzed the data: RA WV IN. Wrote the paper: RA.