About the Authors

William Pontius

Affiliations Department of Physics, Yale University, New Haven, Connecticut, United States of America, Department of Molecular, Cellular, and Developmental Biology, Yale University, New Haven, Connecticut, United States of America

Michael W. Sneddon

Current address: Physical Biosciences Division, Lawrence Berkeley National Lab, Berkeley, California, United States of America.

Affiliations Department of Molecular, Cellular, and Developmental Biology, Yale University, New Haven, Connecticut, United States of America, Interdepartmental Program in Computational Biology and Bioinformatics, Yale University, New Haven, Connecticut, United States of America

Thierry Emonet

thierry.emonet@yale.edu

Affiliations Department of Physics, Yale University, New Haven, Connecticut, United States of America, Department of Molecular, Cellular, and Developmental Biology, Yale University, New Haven, Connecticut, United States of America

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Analyzed the data: WP TE. Contributed reagents/materials/analysis tools: MWS. Wrote the paper: WP TE. Conceived and designed the research: WP TE. Performed the research: WP. Designed and performed the biochemical simulations: WP MWS. Designed the analytical models: WP.