About the Authors

Gabriel Rosser

Affiliation Wolfson Centre for Mathematical Biology, Mathematical Institute, University of Oxford, Radcliffe Observatory Quarter, Oxford, United Kingdom

Alexander G. Fletcher

alexander.fletcher@maths.ox.ac.uk

Affiliation Wolfson Centre for Mathematical Biology, Mathematical Institute, University of Oxford, Radcliffe Observatory Quarter, Oxford, United Kingdom

David A. Wilkinson

Affiliation Oxford Centre for Integrative Systems Biology and Department of Biochemistry, University of Oxford, Oxford, United Kingdom

Jennifer A. de Beyer

Affiliation Oxford Centre for Integrative Systems Biology and Department of Biochemistry, University of Oxford, Oxford, United Kingdom

Christian A. Yates

Affiliation Wolfson Centre for Mathematical Biology, Mathematical Institute, University of Oxford, Radcliffe Observatory Quarter, Oxford, United Kingdom

Judith P. Armitage

Affiliation Oxford Centre for Integrative Systems Biology and Department of Biochemistry, University of Oxford, Oxford, United Kingdom

Philip K. Maini

Affiliation Wolfson Centre for Mathematical Biology, Mathematical Institute, University of Oxford, Radcliffe Observatory Quarter, Oxford, United Kingdom

Ruth E. Baker

Affiliation Wolfson Centre for Mathematical Biology, Mathematical Institute, University of Oxford, Radcliffe Observatory Quarter, Oxford, United Kingdom

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: GR DAW. Performed the experiments: DAW JAdB. Analyzed the data: GR CAY. Contributed reagents/materials/analysis tools: JPA PKM. Wrote the paper: GR. Proposed and developed the analysis methods: GR AGF REB. Conceived and performed the simulation study: GR.