About the Authors
- Lars Ole Schwen
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* E-mail: ole.schwen@mevis.fraunhofer.de
Affiliation Fraunhofer MEVIS, Bremen, Germany
- Markus Krauss
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Affiliations Computational Systems Biology, Bayer Technology Services, Leverkusen, Germany, Aachen Institute for Advanced Study in Computational Engineering Sciences, RWTH Aachen University, Aachen, Germany
- Christoph Niederalt
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Affiliation Computational Systems Biology, Bayer Technology Services, Leverkusen, Germany
- Felix Gremse
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Affiliation Experimental Molecular Imaging, RWTH Aachen University, Aachen, Germany
- Fabian Kiessling
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Affiliation Experimental Molecular Imaging, RWTH Aachen University, Aachen, Germany
- Andrea Schenk
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Affiliation Fraunhofer MEVIS, Bremen, Germany
- Tobias Preusser
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Affiliations Fraunhofer MEVIS, Bremen, Germany, School of Engineering and Science, Jacobs University, Bremen, Germany
- Lars Kuepfer
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Affiliations Computational Systems Biology, Bayer Technology Services, Leverkusen, Germany, Institute of Applied Microbiology, RWTH Aachen University, Aachen, Germany
Competing Interests
I have read the journal's policy and have the following conflicts: MK, CN, and LK are employed by Bayer Technology Services GmbH, the company developing PK-Sim and MoBi.
Author Contributions
Wrote the paper: LOS MK CN FG FK AS TP LK. Performed the micro-CT scans: FG FK. Designed the pharmacokinetic models: MK CN LK. Designed the spatially resolved model: LOS MK CN TP LK. Implemented and performed the spatio-temporal simulations: LOS. Visualized the results: LOS.