Augmenting Microarray Data with Literature-Based Knowledge to Enhance Gene Regulatory Network Inference

Guocai Chen; Michael J. Cairelli; Halil Kilicoglu; Dongwook Shin; Thomas C. Rindflesch

doi:10.1371/journal.pcbi.1003666

Loading metrics

Open Access

Peer-reviewed

Research Article

Augmenting Microarray Data with Literature-Based Knowledge to Enhance Gene Regulatory Network Inference

Guocai Chen ,

Contributed equally to this work with: Guocai Chen, Michael J. Cairelli

Affiliation Lister Hill National Center for Biomedical Communications, National Library of Medicine, Bethesda, Maryland, United States of America
⨯
Michael J. Cairelli ,

Contributed equally to this work with: Guocai Chen, Michael J. Cairelli

* E-mail: mike.cairelli@nih.gov

Affiliation Lister Hill National Center for Biomedical Communications, National Library of Medicine, Bethesda, Maryland, United States of America
⨯
Halil Kilicoglu,

Affiliation Lister Hill National Center for Biomedical Communications, National Library of Medicine, Bethesda, Maryland, United States of America
⨯
Dongwook Shin,

Affiliation Lister Hill National Center for Biomedical Communications, National Library of Medicine, Bethesda, Maryland, United States of America
⨯
Thomas C. Rindflesch

Affiliation Lister Hill National Center for Biomedical Communications, National Library of Medicine, Bethesda, Maryland, United States of America
⨯

Augmenting Microarray Data with Literature-Based Knowledge to Enhance Gene Regulatory Network Inference

Guocai Chen,
Michael J. Cairelli,
Halil Kilicoglu,
Dongwook Shin,
Thomas C. Rindflesch

Published: June 12, 2014
https://doi.org/10.1371/journal.pcbi.1003666

About the Authors

Guocai Chen

Contributed equally to this work with: Guocai Chen, Michael J. Cairelli

Affiliation Lister Hill National Center for Biomedical Communications, National Library of Medicine, Bethesda, Maryland, United States of America

Michael J. Cairelli

Contributed equally to this work with: Guocai Chen, Michael J. Cairelli

* E-mail: mike.cairelli@nih.gov

Affiliation Lister Hill National Center for Biomedical Communications, National Library of Medicine, Bethesda, Maryland, United States of America

Halil Kilicoglu

Affiliation Lister Hill National Center for Biomedical Communications, National Library of Medicine, Bethesda, Maryland, United States of America

Dongwook Shin

Affiliation Lister Hill National Center for Biomedical Communications, National Library of Medicine, Bethesda, Maryland, United States of America

Thomas C. Rindflesch

Affiliation Lister Hill National Center for Biomedical Communications, National Library of Medicine, Bethesda, Maryland, United States of America

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: GC MJC HK TCR. Performed the experiments: GC MJC DS. Analyzed the data: GC MJC. Wrote the paper: GC MJC HK TCR.

Subject Areas
?

For more information about PLOS Subject Areas, click here.
We want your feedback. Do these Subject Areas make sense for this article? Click the target next to the incorrect Subject Area and let us know. Thanks for your help!

Microarrays
Is the Subject Area "Microarrays" applicable to this article?

Thanks for your feedback.
Genetic networks
Is the Subject Area "Genetic networks" applicable to this article?

Thanks for your feedback.
Gene regulatory networks
Is the Subject Area "Gene regulatory networks" applicable to this article?

Thanks for your feedback.
Gene expression
Is the Subject Area "Gene expression" applicable to this article?

Thanks for your feedback.
Genetic algorithms
Is the Subject Area "Genetic algorithms" applicable to this article?

Thanks for your feedback.
Network analysis
Is the Subject Area "Network analysis" applicable to this article?

Thanks for your feedback.
Breast cancer
Is the Subject Area "Breast cancer" applicable to this article?

Thanks for your feedback.
Yeast
Is the Subject Area "Yeast" applicable to this article?

Thanks for your feedback.