Mathematical Modeling Identifies Inhibitors of Apoptosis as Mediators of Positive Feedback and Bistability

Open Access

Peer-reviewed

Research Article

Stefan Legewie ,

*To whom correspondence should be addressed. E-mail: s.legewie@biologie.hu-berlin.de

Affiliation Institute for Theoretical Biology, Humboldt University, Berlin, Germany
⨯
Nils Blüthgen,

Affiliation Institute for Theoretical Biology, Humboldt University, Berlin, Germany
⨯
Hanspeter Herzel

Affiliation Institute for Theoretical Biology, Humboldt University, Berlin, Germany
⨯

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Apoptosis
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Mitochondria
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Signal inhibition
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Apoptotic signaling cascade
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Biochemical simulations
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Protein synthesis
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Protein expression
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Signal amplification
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