Viral Perturbations of Host Networks Reflect Disease Etiology

• Natali Gulbahce ,

  Contributed equally to this work with: Natali Gulbahce, Han Yan

  a Current address: Department of Cellular and Molecular Pharmacology, University of California, San Francisco, California, United States of America

  ¶Member of the Genomic Variation and Network Perturbation Center of Excellence in Genomic Science, Center for Cancer Systems Biology (CCSB), Dana-Farber Cancer Institute, Boston, Massachusetts, United States of America.

  Affiliations Center for Complex Networks Research (CCNR) and Department of Physics, Northeastern University, Boston, Massachusetts, United States of America, Center for Cancer Systems Biology (CCSB) and Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, Massachusetts, United States of America

  ⨯
• Han Yan ,

  Contributed equally to this work with: Natali Gulbahce, Han Yan

  ¶Member of the Genomic Variation and Network Perturbation Center of Excellence in Genomic Science, Center for Cancer Systems Biology (CCSB), Dana-Farber Cancer Institute, Boston, Massachusetts, United States of America.

  Affiliations Center for Cancer Systems Biology (CCSB) and Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, Massachusetts, United States of America, Department of Genetics, Harvard Medical School, Boston, Massachusetts, United States of America

  ⨯
• Amélie Dricot ,

  ¶Member of the Genomic Variation and Network Perturbation Center of Excellence in Genomic Science, Center for Cancer Systems Biology (CCSB), Dana-Farber Cancer Institute, Boston, Massachusetts, United States of America.

  Affiliations Center for Cancer Systems Biology (CCSB) and Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, Massachusetts, United States of America, Department of Genetics, Harvard Medical School, Boston, Massachusetts, United States of America

  ⨯
• Megha Padi ,

  ¶Member of the Genomic Variation and Network Perturbation Center of Excellence in Genomic Science, Center for Cancer Systems Biology (CCSB), Dana-Farber Cancer Institute, Boston, Massachusetts, United States of America.

  Affiliation Center for Cancer Computational Biology (CCCB), Department of Biostatistics and Computational Biology and Department of Cancer Biology, Dana-Farber Cancer Institute and Department of Biostatistics, Harvard School of Public Health, Boston, Massachusetts, United States of America

  ⨯
• Danielle Byrdsong ,

  ¶Member of the Genomic Variation and Network Perturbation Center of Excellence in Genomic Science, Center for Cancer Systems Biology (CCSB), Dana-Farber Cancer Institute, Boston, Massachusetts, United States of America.

  Affiliations Center for Cancer Systems Biology (CCSB) and Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, Massachusetts, United States of America, Department of Genetics, Harvard Medical School, Boston, Massachusetts, United States of America

  ⨯
• Rachel Franchi,

  b Current address: Midwestern University-Arizona College of Osteopathic Medicine, Glendale, Arizona, United States of America

  Affiliations Center for Cancer Systems Biology (CCSB) and Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, Massachusetts, United States of America, Department of Genetics, Harvard Medical School, Boston, Massachusetts, United States of America, Department of Chemistry, Simmons College, Boston, Massachusetts, United States of America

  ⨯
• Deok-Sun Lee,

  Affiliations Center for Complex Networks Research (CCNR) and Department of Physics, Northeastern University, Boston, Massachusetts, United States of America, Department of Natural Medical Sciences and Department of Physics, Inha University, Incheon, Korea

  ⨯
• Orit Rozenblatt-Rosen ,

  ¶Member of the Genomic Variation and Network Perturbation Center of Excellence in Genomic Science, Center for Cancer Systems Biology (CCSB), Dana-Farber Cancer Institute, Boston, Massachusetts, United States of America.

  Affiliation Department of Medical Oncology, Dana-Farber Cancer Institute, and Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, United States of America

  ⨯
• Jessica C. Mar ,

  ¶Member of the Genomic Variation and Network Perturbation Center of Excellence in Genomic Science, Center for Cancer Systems Biology (CCSB), Dana-Farber Cancer Institute, Boston, Massachusetts, United States of America.

  Affiliation Center for Cancer Computational Biology (CCCB), Department of Biostatistics and Computational Biology and Department of Cancer Biology, Dana-Farber Cancer Institute and Department of Biostatistics, Harvard School of Public Health, Boston, Massachusetts, United States of America

  ⨯
• Michael A. Calderwood ,

  ¶Member of the Genomic Variation and Network Perturbation Center of Excellence in Genomic Science, Center for Cancer Systems Biology (CCSB), Dana-Farber Cancer Institute, Boston, Massachusetts, United States of America.

  Affiliations Center for Cancer Systems Biology (CCSB) and Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, Massachusetts, United States of America, Infectious Diseases Division, The Channing Laboratory, Brigham and Women's Hospital and Department of Medicine, Harvard Medical School, Boston, Massachusetts, United States of America

  ⨯
• Amy Baldwin,

  c Current address: Department of Microbiology, School of Medicine, St. George's University, Grenada, West Indies

  Affiliation Infectious Diseases Division, The Channing Laboratory, Brigham and Women's Hospital and Department of Medicine, Harvard Medical School, Boston, Massachusetts, United States of America

  ⨯
• Bo Zhao ,

  ¶Member of the Genomic Variation and Network Perturbation Center of Excellence in Genomic Science, Center for Cancer Systems Biology (CCSB), Dana-Farber Cancer Institute, Boston, Massachusetts, United States of America.

  Affiliation Infectious Diseases Division, The Channing Laboratory, Brigham and Women's Hospital and Department of Medicine, Harvard Medical School, Boston, Massachusetts, United States of America

  ⨯
• Balaji Santhanam,

  Affiliations Center for Cancer Systems Biology (CCSB) and Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, Massachusetts, United States of America, Department of Genetics, Harvard Medical School, Boston, Massachusetts, United States of America

  ⨯
• Pascal Braun,

  Affiliations Center for Cancer Systems Biology (CCSB) and Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, Massachusetts, United States of America, Department of Genetics, Harvard Medical School, Boston, Massachusetts, United States of America

  ⨯
• Nicolas Simonis,

  d Current address: Laboratoire de Bioinformatique des Génomes et des Réseaux, Université Libre de Bruxelles, Bruxelles, Belgium

  Affiliations Center for Cancer Systems Biology (CCSB) and Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, Massachusetts, United States of America, Department of Genetics, Harvard Medical School, Boston, Massachusetts, United States of America

  ⨯
• Kyung-Won Huh,

  e Current address: Department of Biochemistry and Molecular Biology, Louisiana State University Health Science Center, New Orleans, Louisiana, United States of America

  Affiliation Infectious Diseases Division, The Channing Laboratory, Brigham and Women's Hospital and Department of Medicine, Harvard Medical School, Boston, Massachusetts, United States of America

  ⨯
• Karin Hellner ,

  ¶Member of the Genomic Variation and Network Perturbation Center of Excellence in Genomic Science, Center for Cancer Systems Biology (CCSB), Dana-Farber Cancer Institute, Boston, Massachusetts, United States of America.

  Affiliation Infectious Diseases Division, The Channing Laboratory, Brigham and Women's Hospital and Department of Medicine, Harvard Medical School, Boston, Massachusetts, United States of America

  ⨯
• Miranda Grace ,

  ¶Member of the Genomic Variation and Network Perturbation Center of Excellence in Genomic Science, Center for Cancer Systems Biology (CCSB), Dana-Farber Cancer Institute, Boston, Massachusetts, United States of America.

  Affiliation Infectious Diseases Division, The Channing Laboratory, Brigham and Women's Hospital and Department of Medicine, Harvard Medical School, Boston, Massachusetts, United States of America

  ⨯
• Alyce Chen ,

  ¶Member of the Genomic Variation and Network Perturbation Center of Excellence in Genomic Science, Center for Cancer Systems Biology (CCSB), Dana-Farber Cancer Institute, Boston, Massachusetts, United States of America.

  Affiliation Infectious Diseases Division, The Channing Laboratory, Brigham and Women's Hospital and Department of Medicine, Harvard Medical School, Boston, Massachusetts, United States of America

  ⨯
• Renee Rubio ,

  ¶Member of the Genomic Variation and Network Perturbation Center of Excellence in Genomic Science, Center for Cancer Systems Biology (CCSB), Dana-Farber Cancer Institute, Boston, Massachusetts, United States of America.

  Affiliation Center for Cancer Computational Biology (CCCB), Department of Biostatistics and Computational Biology and Department of Cancer Biology, Dana-Farber Cancer Institute and Department of Biostatistics, Harvard School of Public Health, Boston, Massachusetts, United States of America

  ⨯
• Jarrod A. Marto ,

  ¶Member of the Genomic Variation and Network Perturbation Center of Excellence in Genomic Science, Center for Cancer Systems Biology (CCSB), Dana-Farber Cancer Institute, Boston, Massachusetts, United States of America.

  Affiliation Blais Proteomics Center and Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, Massachusetts, United States of America

  ⨯
• Nicholas A. Christakis,

  Affiliation Department of Health Care Policy, Harvard Medical School and Department of Sociology, Harvard University, Cambridge, Massachusetts, United States of America

  ⨯
• Elliott Kieff ,

  ¶Member of the Genomic Variation and Network Perturbation Center of Excellence in Genomic Science, Center for Cancer Systems Biology (CCSB), Dana-Farber Cancer Institute, Boston, Massachusetts, United States of America.

  Affiliation Infectious Diseases Division, The Channing Laboratory, Brigham and Women's Hospital and Department of Medicine, Harvard Medical School, Boston, Massachusetts, United States of America

  ⨯
• Frederick P. Roth ,

  f Current address: Donnelly Centre for Cellular and Biomolecular Research, University of Toronto, Toronto, Ontario, Canada and Samuel Lunenfeld Research Institute, Mt. Sinai Hospital, Toronto, Ontario, Canada

  ¶Member of the Genomic Variation and Network Perturbation Center of Excellence in Genomic Science, Center for Cancer Systems Biology (CCSB), Dana-Farber Cancer Institute, Boston, Massachusetts, United States of America.

  Affiliations Center for Cancer Systems Biology (CCSB) and Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, Massachusetts, United States of America, Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, Massachusetts, United States of America

  ⨯
• Jennifer Roecklein-Canfield,

  Affiliations Center for Cancer Systems Biology (CCSB) and Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, Massachusetts, United States of America, Department of Genetics, Harvard Medical School, Boston, Massachusetts, United States of America, Department of Chemistry, Simmons College, Boston, Massachusetts, United States of America

  ⨯
• James A. DeCaprio ,

  ¶Member of the Genomic Variation and Network Perturbation Center of Excellence in Genomic Science, Center for Cancer Systems Biology (CCSB), Dana-Farber Cancer Institute, Boston, Massachusetts, United States of America.

  Affiliation Department of Medical Oncology, Dana-Farber Cancer Institute, and Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, United States of America

  ⨯
• Michael E. Cusick ,

  ¶Member of the Genomic Variation and Network Perturbation Center of Excellence in Genomic Science, Center for Cancer Systems Biology (CCSB), Dana-Farber Cancer Institute, Boston, Massachusetts, United States of America.

  Affiliations Center for Cancer Systems Biology (CCSB) and Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, Massachusetts, United States of America, Department of Genetics, Harvard Medical School, Boston, Massachusetts, United States of America

  ⨯
• John Quackenbush ,

  ¶Member of the Genomic Variation and Network Perturbation Center of Excellence in Genomic Science, Center for Cancer Systems Biology (CCSB), Dana-Farber Cancer Institute, Boston, Massachusetts, United States of America.

  Affiliation Center for Cancer Computational Biology (CCCB), Department of Biostatistics and Computational Biology and Department of Cancer Biology, Dana-Farber Cancer Institute and Department of Biostatistics, Harvard School of Public Health, Boston, Massachusetts, United States of America

  ⨯
• David E. Hill ,

  ¶Member of the Genomic Variation and Network Perturbation Center of Excellence in Genomic Science, Center for Cancer Systems Biology (CCSB), Dana-Farber Cancer Institute, Boston, Massachusetts, United States of America.

  Affiliations Center for Cancer Systems Biology (CCSB) and Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, Massachusetts, United States of America, Department of Genetics, Harvard Medical School, Boston, Massachusetts, United States of America

  ⨯
• Karl Münger ,

  ¶Member of the Genomic Variation and Network Perturbation Center of Excellence in Genomic Science, Center for Cancer Systems Biology (CCSB), Dana-Farber Cancer Institute, Boston, Massachusetts, United States of America.

  Affiliation Infectious Diseases Division, The Channing Laboratory, Brigham and Women's Hospital and Department of Medicine, Harvard Medical School, Boston, Massachusetts, United States of America

  ⨯
• Marc Vidal ,

  * E-mail: marc_vidal@dfci.harvard.edu (MV); alb@neu.edu (ALB)

  ¶Member of the Genomic Variation and Network Perturbation Center of Excellence in Genomic Science, Center for Cancer Systems Biology (CCSB), Dana-Farber Cancer Institute, Boston, Massachusetts, United States of America.

  Affiliations Center for Cancer Systems Biology (CCSB) and Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, Massachusetts, United States of America, Department of Genetics, Harvard Medical School, Boston, Massachusetts, United States of America

  ⨯
•  [ ... ],
• Albert-László Barabási

  * E-mail: marc_vidal@dfci.harvard.edu (MV); alb@neu.edu (ALB)

  ¶Member of the Genomic Variation and Network Perturbation Center of Excellence in Genomic Science, Center for Cancer Systems Biology (CCSB), Dana-Farber Cancer Institute, Boston, Massachusetts, United States of America.

  Affiliations Center for Complex Networks Research (CCNR) and Department of Physics, Northeastern University, Boston, Massachusetts, United States of America, Center for Cancer Systems Biology (CCSB) and Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, Massachusetts, United States of America, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, United States of America

  ⨯
• [ view all ]
• [ view less ]