Genome-Wide Signatures of Transcription Factor Activity: Connecting Transcription Factors, Disease, and Small Molecules

• Jing Chen ,

  Contributed equally to this work with: Jing Chen, Zhen Hu, Mukta Phatak

  Affiliation Laboratory for Statistical Genomics and Systems Biology, Department of Environmental Health, University of Cincinnati College of Medicine, Cincinnati, Ohio, United States of America

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• Zhen Hu ,

  Contributed equally to this work with: Jing Chen, Zhen Hu, Mukta Phatak

  Affiliation Laboratory for Statistical Genomics and Systems Biology, Department of Environmental Health, University of Cincinnati College of Medicine, Cincinnati, Ohio, United States of America

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• Mukta Phatak ,

  Contributed equally to this work with: Jing Chen, Zhen Hu, Mukta Phatak

  Affiliation Laboratory for Statistical Genomics and Systems Biology, Department of Environmental Health, University of Cincinnati College of Medicine, Cincinnati, Ohio, United States of America

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• John Reichard,

  Affiliations Department of Environmental Health, University of Cincinnati, Cincinnati, Ohio, United States of America, Toxicology Excellence for Risk Assessment (TERA), Cincinnati, Ohio, United States of America

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• Johannes M. Freudenberg,

  Current address: Computational Biology, Quantitative Sciences, Medicines Discovery and Development, GlaxoSmithKline, Research Triangle Park, North Carolina, United States of America.

  Affiliation Laboratory for Statistical Genomics and Systems Biology, Department of Environmental Health, University of Cincinnati College of Medicine, Cincinnati, Ohio, United States of America

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• Siva Sivaganesan,

  Affiliation Mathematical Sciences Department, University of Cincinnati, Cincinnati, Ohio, United States of America

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• Mario Medvedovic

  * E-mail: medvedm@ucmail.uc.edu

  Affiliation Laboratory for Statistical Genomics and Systems Biology, Department of Environmental Health, University of Cincinnati College of Medicine, Cincinnati, Ohio, United States of America

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