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Limited Agreement of Independent RNAi Screens for Virus-Required Host Genes Owes More to False-Negative than False-Positive Factors

  • Linhui Hao ,

    Contributed equally to this work with: Linhui Hao, Qiuling He

    Affiliations Institute of Molecular Virology, University of Wisconsin-Madison, Madison, Wisconsin, United States of America, Howard Hughes Medical Institute, University of Wisconsin-Madison, Madison, Wisconsin, United States of America

  • Qiuling He ,

    Contributed equally to this work with: Linhui Hao, Qiuling He

    Current address: Novartis Institute of Biomedical Research, Boston, Massachusetts, United States of America.

    Affiliation Department of Statistics, University of Wisconsin-Madison, Madison, Wisconsin, United States of America

  • Zhishi Wang,

    Affiliation Department of Statistics, University of Wisconsin-Madison, Madison, Wisconsin, United States of America

  • Mark Craven,

    Affiliations Department of Biostatistics and Medical Informatics, University of Wisconsin-Madison, Madison, Wisconsin, United States of America, Department of Computer Sciences, University of Wisconsin-Madison, Madison, Wisconsin, United States of America

  • Michael A. Newton ,

    newton@biostat.wisc.edu (MAN); ahlquist@wisc.edu (PA)

    Affiliations Department of Statistics, University of Wisconsin-Madison, Madison, Wisconsin, United States of America, Department of Biostatistics and Medical Informatics, University of Wisconsin-Madison, Madison, Wisconsin, United States of America

  • Paul Ahlquist

    newton@biostat.wisc.edu (MAN); ahlquist@wisc.edu (PA)

    Affiliations Institute of Molecular Virology, University of Wisconsin-Madison, Madison, Wisconsin, United States of America, Howard Hughes Medical Institute, University of Wisconsin-Madison, Madison, Wisconsin, United States of America, Morgridge Institute for Research, Madison, Wisconsin, United States of America

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