About the Authors

Kai Xia

Contributed equally to this work with: Kai Xia, Huiling Xue, Dong Dong, Shanshan Zhu

Affiliation The Chinese Academy of Sciences Key Laboratory of Developmental Biology, Center for Molecular Systems Biology, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing, People's Republic of China

Huiling Xue

Contributed equally to this work with: Kai Xia, Huiling Xue, Dong Dong, Shanshan Zhu

Affiliation The Chinese Academy of Sciences Key Laboratory of Developmental Biology, Center for Molecular Systems Biology, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing, People's Republic of China

Dong Dong

Contributed equally to this work with: Kai Xia, Huiling Xue, Dong Dong, Shanshan Zhu

Affiliation The Chinese Academy of Sciences Key Laboratory of Developmental Biology, Center for Molecular Systems Biology, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing, People's Republic of China

Shanshan Zhu

Contributed equally to this work with: Kai Xia, Huiling Xue, Dong Dong, Shanshan Zhu

Affiliation The Chinese Academy of Sciences Key Laboratory of Developmental Biology, Center for Molecular Systems Biology, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing, People's Republic of China

Jiamu Wang

Affiliation The Chinese Academy of Sciences Key Laboratory of Developmental Biology, Center for Molecular Systems Biology, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing, People's Republic of China

Qingpeng Zhang

Affiliation The Chinese Academy of Sciences Key Laboratory of Developmental Biology, Center for Molecular Systems Biology, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing, People's Republic of China

Lei Hou

Affiliation The Chinese Academy of Sciences Key Laboratory of Developmental Biology, Center for Molecular Systems Biology, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing, People's Republic of China

Hua Chen

Affiliation The State Key Laboratory of Biomembrane and Membrane Biotechnology, Department of Biological Sciences and Biotechnology, Tsinghua University, Beijing, People's Republic of China

Ran Tao

Affiliation The State Key Laboratory of Biomembrane and Membrane Biotechnology, Department of Biological Sciences and Biotechnology, Tsinghua University, Beijing, People's Republic of China

Zheng Huang

Affiliation The Chinese Academy of Sciences Key Laboratory of Developmental Biology, Center for Molecular Systems Biology, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing, People's Republic of China

Zheng Fu

Affiliation The Chinese Academy of Sciences Key Laboratory of Developmental Biology, Center for Molecular Systems Biology, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing, People's Republic of China

Ye-Guang Chen

Affiliation The State Key Laboratory of Biomembrane and Membrane Biotechnology, Department of Biological Sciences and Biotechnology, Tsinghua University, Beijing, People's Republic of China

Jing-Dong J Han

To whom correspondence should be addressed. E-mail: jdhan@genetics.ac.cn

Affiliation The Chinese Academy of Sciences Key Laboratory of Developmental Biology, Center for Molecular Systems Biology, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing, People's Republic of China

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

JDJH conceived and directed the project and designed the analyses. KX, HX, DD, SZ, QZ, and LH performed the analyses. ZF contributed materials and analysis tools. YGC and JDJH wrote the paper. KX, HX, DD, SZ, JW, HC, RT, and ZH annotated the interaction directions according to the literature.