About the Authors
- Ji Lee
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Affiliations Department of Computational Biology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, United States of America , Department of Bioengineering, Pennsylvania State University, University Park, Pennsylvania, United States of America
- Zhihua Li
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Affiliation Department of Computational Biology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, United States of America
- Rachel Brower-Sinning
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Affiliation Department of Computational Biology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, United States of America
- Bino John
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*To whom correspondence should be addressed. E-mail: john@johnlab.org
Affiliations Department of Computational Biology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, United States of America , University of Pittsburgh Cancer Institute, Pittsburgh, Pennsylvania, United States of America
Competing Interests
The authors have declared that no competing interests exist.
Author Contributions
JL implemented the K-Factor algorithm in Java, generated results, and contributed to writing the manuscript. ZL analyzed the core results and computationally identified specific CRMs. RBS was involved in benchmarking the performance of K-Factor. BJ conceived the project, designed and implemented the underlying methods and datasets, generated results, wrote the manuscript, and supervised the project.