Frequent Gain and Loss of Functional Transcription Factor Binding Sites

Scott W Doniger; Justin C Fay

doi:10.1371/journal.pcbi.0030099

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Open Access

Peer-reviewed

Research Article

Frequent Gain and Loss of Functional Transcription Factor Binding Sites

Scott W Doniger,

Affiliation Computational Biology Program, Washington University School of Medicine, St. Louis, Missouri, United States of America
⨯
Justin C Fay

*To whom correspondence should be addressed. E-mail: jfay@genetics.wustl.edu

Affiliations Computational Biology Program, Washington University School of Medicine, St. Louis, Missouri, United States of America , Department of Genetics, Washington University School of Medicine, St. Louis, Missouri, United States of America
⨯

Frequent Gain and Loss of Functional Transcription Factor Binding Sites

Scott W Doniger,
Justin C Fay

Published: May 25, 2007
https://doi.org/10.1371/journal.pcbi.0030099

About the Authors

Scott W Doniger

Affiliation Computational Biology Program, Washington University School of Medicine, St. Louis, Missouri, United States of America

Justin C Fay

*To whom correspondence should be addressed. E-mail: jfay@genetics.wustl.edu

Affiliations Computational Biology Program, Washington University School of Medicine, St. Louis, Missouri, United States of America , Department of Genetics, Washington University School of Medicine, St. Louis, Missouri, United States of America

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

SWD and JCF conceived and designed the experiments. SWD performed the experiments, analyzed the data, and wrote the paper.

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Transcription factors
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Gene expression
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Saccharomyces cerevisiae
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Sequence alignment
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Gene regulation
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Binding analysis
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Conservation science
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Evolutionary genetics
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