About the Authors

Jiang Du

Affiliation Department of Computer Science, Yale University, New Haven, Connecticut, United States of America

Robert D. Bjornson

Affiliations Department of Computer Science, Yale University, New Haven, Connecticut, United States of America, Keck Biotechnology Resource Laboratory, Yale University, New Haven, Connecticut, United States of America

Zhengdong D. Zhang

Affiliation Department of Molecular Biophysics and Biochemistry, Yale University, New Haven, Connecticut, United States of America

Yong Kong

Affiliation Keck Biotechnology Resource Laboratory, Yale University, New Haven, Connecticut, United States of America

Michael Snyder

Affiliations Department of Molecular Biophysics and Biochemistry, Yale University, New Haven, Connecticut, United States of America, Department of Molecular, Cellular and Developmental Biology, Yale University, New Haven, Connecticut, United States of America

Mark B. Gerstein

Mark.Gerstein@yale.edu

Affiliations Department of Computer Science, Yale University, New Haven, Connecticut, United States of America, Department of Molecular Biophysics and Biochemistry, Yale University, New Haven, Connecticut, United States of America, Program in Computational Biology and Bioinformatics, Yale University, New Haven, Connecticut, United States of America

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: JD RDB ZDZ MBG. Performed the experiments: JD. Analyzed the data: JD RDB ZDZ YK MS MBG. Contributed reagents/materials/analysis tools: JD RDB. Wrote the paper: JD MBG.