About the Authors

Matthew D. Christensen

Affiliation Department of Internal Medicine, Division of Cardiovascular Medicine, University of Iowa Carver College of Medicine, Iowa City, Iowa, United States of America

Wen Dun

Affiliation Department of Pharmacology, Center for Molecular Therapeutics, Columbia University, New York, New York, United States of America

Penelope A. Boyden

Affiliation Department of Pharmacology, Center for Molecular Therapeutics, Columbia University, New York, New York, United States of America

Mark E. Anderson

Affiliations Department of Internal Medicine, Division of Cardiovascular Medicine, University of Iowa Carver College of Medicine, Iowa City, Iowa, United States of America, Department of Molecular Physiology and Biophysics, University of Iowa Carver College of Medicine, Iowa City, Iowa, United States of America

Peter J. Mohler

Affiliations Department of Internal Medicine, Division of Cardiovascular Medicine, University of Iowa Carver College of Medicine, Iowa City, Iowa, United States of America, Department of Molecular Physiology and Biophysics, University of Iowa Carver College of Medicine, Iowa City, Iowa, United States of America

Thomas J. Hund

thomas-hund@uiowa.edu

Affiliation Department of Internal Medicine, Division of Cardiovascular Medicine, University of Iowa Carver College of Medicine, Iowa City, Iowa, United States of America

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: MDC PAB TJH. Performed the experiments: MDC WD PAB TJH. Analyzed the data: MDC MEA PJM TJH. Contributed reagents/materials/analysis tools: MDC WD PAB MEA PJM TJH. Wrote the paper: MDC PAB MEA PJM TJH.