About the Authors

Peter Buske

Contributed equally to this work with: Peter Buske, Jörg Galle

buske@izbi.uni-leipzig.de

Affiliation Interdisciplinary Centre for Bioinformatics, University Leipzig, Leipzig, Germany

Jörg Galle

Contributed equally to this work with: Peter Buske, Jörg Galle

Affiliation Interdisciplinary Centre for Bioinformatics, University Leipzig, Leipzig, Germany

Nick Barker

Affiliation Hubrecht Institute, University Medical Center, Utrecht, The Netherlands

Gabriela Aust

Affiliation Center of Surgery, Research Laboratories, University Leipzig, Leipzig, Germany

Hans Clevers

Affiliation Hubrecht Institute, University Medical Center, Utrecht, The Netherlands

Markus Loeffler

Affiliations Interdisciplinary Centre for Bioinformatics, University Leipzig, Leipzig, Germany, Institute for Medical Informatics, Statistics and Epidemiology, University Leipzig, Leipzig, Germany

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: NB HC. Performed the experiments: NB GA. Analyzed the data: PB JG. Wrote the paper: JG ML. Performed all simulations: PB. Designed the model: JG. Provided essential ideas regarding the model design: HC ML.