Warm Body Temperature Facilitates Energy Efficient Cortical Action Potentials

Yuguo Yu; Adam P. Hill; David A. McCormick

doi:10.1371/journal.pcbi.1002456

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Open Access

Peer-reviewed

Research Article

Warm Body Temperature Facilitates Energy Efficient Cortical Action Potentials

Yuguo Yu,

Affiliations Department of Neurobiology and Kavli Institute for Neuroscience, Yale University School of Medicine, New Haven, Connecticut, United States of America, Center for Computational Systems Biology, Fudan University, Shanghai, People's Republic of China
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Adam P. Hill,

Affiliation Department of Neurobiology and Kavli Institute for Neuroscience, Yale University School of Medicine, New Haven, Connecticut, United States of America
⨯
David A. McCormick

* E-mail: David.mccormick@yale.edu

Affiliation Department of Neurobiology and Kavli Institute for Neuroscience, Yale University School of Medicine, New Haven, Connecticut, United States of America
⨯

Warm Body Temperature Facilitates Energy Efficient Cortical Action Potentials

Yuguo Yu,
Adam P. Hill,
David A. McCormick

Published: April 12, 2012
https://doi.org/10.1371/journal.pcbi.1002456

About the Authors

Yuguo Yu

Affiliations Department of Neurobiology and Kavli Institute for Neuroscience, Yale University School of Medicine, New Haven, Connecticut, United States of America, Center for Computational Systems Biology, Fudan University, Shanghai, People's Republic of China

Adam P. Hill

Affiliation Department of Neurobiology and Kavli Institute for Neuroscience, Yale University School of Medicine, New Haven, Connecticut, United States of America

David A. McCormick

* E-mail: David.mccormick@yale.edu

Affiliation Department of Neurobiology and Kavli Institute for Neuroscience, Yale University School of Medicine, New Haven, Connecticut, United States of America

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: YY APH DAM. Performed the experiments: YY APH. Analyzed the data: YY APH. Contributed reagents/materials/analysis tools: YY. Wrote the paper: YY DAM. Performed the computational model study: YY.

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Action potentials
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Neurons
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Body temperature
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Axons
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Membrane potential
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Oxygen
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Pyramidal cells
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Squids
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