About the Authors

Sagar D Khare

Affiliation Department of Biochemistry and Biophysics, University of North Carolina, Chapel Hill, North Carolina, United States of America

Feng Ding

Affiliation Department of Biochemistry and Biophysics, University of North Carolina, Chapel Hill, North Carolina, United States of America

Kenneth N Gwanmesia

Affiliations Department of Biochemistry and Biophysics, University of North Carolina, Chapel Hill, North Carolina, United States of America , Department of Physics and Pre-Engineering, Delaware State University, Dover, Delaware, United States of America

Nikolay V Dokholyan

To whom correspondence should be addressed. E-mail: dokh@med.unc.edu

Affiliation Department of Biochemistry and Biophysics, University of North Carolina, Chapel Hill, North Carolina, United States of America

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

SDK, FD, and NVD conceived and designed the experiments. SDK, FD, and KNG performed the experiments. SDK, FD, and NVD analyzed the data. SDK and NVD wrote the paper.