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Research Article

Modeling the Amplification Dynamics of Human Alu Retrotransposons

  • Dale J Hedges equal contributor,

    equal contributor Contributed equally to this work with: Dale J Hedges, Richard Cordaux

    Affiliation: Department of Biological Sciences, Biological Computation and Visualization Center, Center for Bio-Modular Microsystems, Louisiana State University, Baton Rouge, Louisiana, United States of America

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  • Richard Cordaux equal contributor,

    equal contributor Contributed equally to this work with: Dale J Hedges, Richard Cordaux

    Affiliation: Department of Biological Sciences, Biological Computation and Visualization Center, Center for Bio-Modular Microsystems, Louisiana State University, Baton Rouge, Louisiana, United States of America

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  • Jinchuan Xing,

    Affiliation: Department of Biological Sciences, Biological Computation and Visualization Center, Center for Bio-Modular Microsystems, Louisiana State University, Baton Rouge, Louisiana, United States of America

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  • David J Witherspoon,

    Affiliation: Department of Human Genetics, University of Utah Health Sciences Center, Salt Lake City, Utah, United States of America

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  • Alan R Rogers,

    Affiliation: Department of Anthropology, University of Utah, Salt Lake City, Utah, United States of America

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  • Lynn B Jorde,

    Affiliation: Department of Human Genetics, University of Utah Health Sciences Center, Salt Lake City, Utah, United States of America

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  • Mark A Batzer mail

    To whom correspondence should be addressed. E-mail: mbatzer@lsu.edu

    Affiliation: Department of Biological Sciences, Biological Computation and Visualization Center, Center for Bio-Modular Microsystems, Louisiana State University, Baton Rouge, Louisiana, United States of America

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  • Published: September 30, 2005
  • DOI: 10.1371/journal.pcbi.0010044

About the Authors

Dale J Hedges, Richard Cordaux, Jinchuan Xing, Mark A Batzer
Department of Biological Sciences, Biological Computation and Visualization Center, Center for Bio-Modular Microsystems, Louisiana State University, Baton Rouge, Louisiana, United States of America
David J Witherspoon, Lynn B Jorde
Department of Human Genetics, University of Utah Health Sciences Center, Salt Lake City, Utah, United States of America
Alan R Rogers
Department of Anthropology, University of Utah, Salt Lake City, Utah, United States of America

Corresponding Author

Email: mbatzer@lsu.edu

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

DJH and RC conceived and designed the experiments. DJH performed the experiments. DJH, RC, JX, DJW, ARR, LBJ, and MAB analyzed the data. LBJ and MAB contributed reagents/materials/analysis tools. DJH and RC wrote the paper.