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Research Article

Entropic Stabilization of Proteins and Its Proteomic Consequences

  • Igor N Berezovsky,

    Affiliation: Department of Chemistry and Chemical Biology, Harvard University, Cambridge, Massachusetts, United States of America

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  • William W Chen,

    Affiliations: Department of Chemistry and Chemical Biology, Harvard University, Cambridge, Massachusetts, United States of America, Department of Biophysics, Harvard University, Cambridge, Massachusetts, United States of America

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  • Paul J Choi,

    Affiliation: Department of Chemistry and Chemical Biology, Harvard University, Cambridge, Massachusetts, United States of America

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  • Eugene I Shakhnovich mail

    To whom correspondence should be addressed. E-mail: eugene@belok.harvard.edu

    Affiliation: Department of Chemistry and Chemical Biology, Harvard University, Cambridge, Massachusetts, United States of America

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  • Published: September 30, 2005
  • DOI: 10.1371/journal.pcbi.0010047

About the Authors

Igor N Berezovsky, William W Chen, Paul J Choi, Eugene I Shakhnovich
Department of Chemistry and Chemical Biology, Harvard University, Cambridge, Massachusetts, United States of America
William W Chen
Department of Biophysics, Harvard University, Cambridge, Massachusetts, United States of America

Corresponding Author

Email: eugene@belok.harvard.edu

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

INB, PJC, and EIS performed the experiments. INB, WWC, and EIS analyzed the data. PJC contributed reagents/materials/analysis tools. INB and EIS wrote the paper.