About the Authors

Eric D Scheeff

To whom correspondence should be addressed. E-mail: escheeff@sdsc.edu

Affiliation San Diego Supercomputer Center, University of California, San Diego, California, United States of America

Philip E Bourne

Affiliations San Diego Supercomputer Center, University of California, San Diego, California, United States of America , Department of Pharmacology, University of California, San Diego, California, United States of America

Competing Interests

The co-author of this manuscript is the editor-in-chief of PLoS Computational Biology.

Author Contributions

EDS and PEB conceived and designed the experiments. EDS performed the experiments, analyzed the data, and wrote the paper.