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Research Article

SNPdetector: A Software Tool for Sensitive and Accurate SNP Detection

  • Jinghui Zhang mail,

    To whom correspondence should be addressed. E-mail: jinghuiz@mail.nih.gov

    Affiliation: Laboratory of Population Genetics, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, United States of America

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  • David A Wheeler,

    Affiliation: Human Genome Sequencing Center and Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, Texas, United States of America

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  • Imtiaz Yakub,

    Affiliation: Human Genome Sequencing Center and Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, Texas, United States of America

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  • Sharon Wei,

    Affiliation: Human Genome Sequencing Center and Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, Texas, United States of America

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  • Raman Sood,

    Affiliation: Genetics and Molecular Biology Branch, National Human Genome Research Institute, National Institutes of Health, Bethesda, Maryland, United States of America

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  • William Rowe,

    Affiliation: Laboratory of Population Genetics, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, United States of America

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  • Paul P Liu,

    Affiliation: Genetics and Molecular Biology Branch, National Human Genome Research Institute, National Institutes of Health, Bethesda, Maryland, United States of America

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  • Richard A Gibbs,

    Affiliation: Human Genome Sequencing Center and Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, Texas, United States of America

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  • Kenneth H Buetow

    Affiliation: Laboratory of Population Genetics, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, United States of America

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  • Published: October 28, 2005
  • DOI: 10.1371/journal.pcbi.0010053

About the Authors

Jinghui Zhang, William Rowe, Kenneth H Buetow
Laboratory of Population Genetics, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, United States of America
David A Wheeler, Imtiaz Yakub, Sharon Wei, Richard A Gibbs
Human Genome Sequencing Center and Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, Texas, United States of America
Raman Sood, Paul P Liu
Genetics and Molecular Biology Branch, National Human Genome Research Institute, National Institutes of Health, Bethesda, Maryland, United States of America

Corresponding Author

Email: jinghuiz@mail.nih.gov

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

JZ conceived and designed the experiments, developed the software tool, and performed testing. WR implemented the software. JZ, DAW, IY, SW, RS, and PPL analyzed the data. JZ, PPL, RAG, and KHB contributed reagents/materials/analysis tools. JZ, DAW, and RS wrote the paper.