About the Authors

Jinghui Zhang

To whom correspondence should be addressed. E-mail: jinghuiz@mail.nih.gov

Affiliation Laboratory of Population Genetics, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, United States of America

David A Wheeler

Affiliation Human Genome Sequencing Center and Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, Texas, United States of America

Imtiaz Yakub

Affiliation Human Genome Sequencing Center and Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, Texas, United States of America

Sharon Wei

Affiliation Human Genome Sequencing Center and Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, Texas, United States of America

Raman Sood

Affiliation Genetics and Molecular Biology Branch, National Human Genome Research Institute, National Institutes of Health, Bethesda, Maryland, United States of America

William Rowe

Affiliation Laboratory of Population Genetics, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, United States of America

Paul P Liu

Affiliation Genetics and Molecular Biology Branch, National Human Genome Research Institute, National Institutes of Health, Bethesda, Maryland, United States of America

Richard A Gibbs

Affiliation Human Genome Sequencing Center and Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, Texas, United States of America

Kenneth H Buetow

Affiliation Laboratory of Population Genetics, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, United States of America

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

JZ conceived and designed the experiments, developed the software tool, and performed testing. WR implemented the software. JZ, DAW, IY, SW, RS, and PPL analyzed the data. JZ, PPL, RAG, and KHB contributed reagents/materials/analysis tools. JZ, DAW, and RS wrote the paper.