About the Authors
- Eli S Groban
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Contributed equally to this work with: Eli S Groban, Arjun Narayanan
Affiliations Department of Pharmaceutical Chemistry, University of California San Francisco, San Francisco, California, United States of America , Graduate Group in Biophysics, University of California San Francisco, San Francisco, California, United States of America
- Arjun Narayanan
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Contributed equally to this work with: Eli S Groban, Arjun Narayanan
Affiliations Department of Pharmaceutical Chemistry, University of California San Francisco, San Francisco, California, United States of America , Graduate Group in Biophysics, University of California San Francisco, San Francisco, California, United States of America
- Matthew P Jacobson
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*To whom correspondence should be addressed. E-mail: matt@cgl.ucsf.edu
Affiliations Department of Pharmaceutical Chemistry, University of California San Francisco, San Francisco, California, United States of America , Graduate Group in Biophysics, University of California San Francisco, San Francisco, California, United States of America
Competing Interests
MPJ is a member of the Scientific Advisory Board of Schrodinger, Inc., a company that distributes scientific software, including software that he has written. However, MPJ states that he believes that the work described in this manuscript has no significant commercial value, since the study is concerned with a fundamental problem in biophysics (i.e., it is unrelated to drug discovery, which is the company's focus).
Author Contributions
MPJ conceived and designed the experiments. ESG, AN, and MPJ performed the experiments. ESG, AN, and MPJ analyzed the data. ESG, AN, and MPJ wrote the paper.