Reverse Engineering the Gap Gene Network of Drosophila melanogaster

Theodore J Perkins; Johannes Jaeger; John Reinitz; Leon Glass

doi:10.1371/journal.pcbi.0020051

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Open Access

Peer-reviewed

Research Article

Reverse Engineering the Gap Gene Network of Drosophila melanogaster

Theodore J Perkins ,

*To whom correspondence should be addressed. E-mail: perkins@mcb.mcgill.ca

Affiliation McGill Centre for Bioinformatics, McGill University, Montreal, Quebec, Canada
⨯
Johannes Jaeger,

¤ Current address: Department of Zoology, University of Cambridge, Cambridge, United Kingdom

Affiliations Department of Applied Mathematics and Statistics, Stony Brook University, Stony Brook, New York, United States of America , Center for Developmental Genetics, Stony Brook University, Stony Brook, New York, United States of America
⨯
John Reinitz,

Affiliations Department of Applied Mathematics and Statistics, Stony Brook University, Stony Brook, New York, United States of America , Center for Developmental Genetics, Stony Brook University, Stony Brook, New York, United States of America
⨯
Leon Glass

Affiliation Centre for Nonlinear Dynamics, Department of Physiology, McGill University, Montreal, Quebec, Canada
⨯

Reverse Engineering the Gap Gene Network of Drosophila melanogaster

Theodore J Perkins,
Johannes Jaeger,
John Reinitz,
Leon Glass

Published: May 19, 2006
https://doi.org/10.1371/journal.pcbi.0020051

About the Authors

Theodore J Perkins

*To whom correspondence should be addressed. E-mail: perkins@mcb.mcgill.ca

Affiliation McGill Centre for Bioinformatics, McGill University, Montreal, Quebec, Canada

Johannes Jaeger

¤ Current address: Department of Zoology, University of Cambridge, Cambridge, United Kingdom

Affiliations Department of Applied Mathematics and Statistics, Stony Brook University, Stony Brook, New York, United States of America , Center for Developmental Genetics, Stony Brook University, Stony Brook, New York, United States of America

John Reinitz

Leon Glass

Affiliation Centre for Nonlinear Dynamics, Department of Physiology, McGill University, Montreal, Quebec, Canada

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

TJP, JJ, JR, and LG analyzed the data. JJ contributed reagents/materials/analysis tools. TJP, JJ, JR, and LG wrote the paper.

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Gene regulation
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Gene expression
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Synthetic genetic networks
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Genetic networks
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Drosophila melanogaster
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Optimization
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Embryos
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Partial differential equations
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