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Research Article

How Does Cross-Reactive Stimulation Affect the Longevity of CD8+ T Cell Memory?

  • Vitaly V Ganusov equal contributor,

    equal contributor Contributed equally to this work with: Vitaly V Ganusov, Rustom Antia

    Affiliation: Department of Biology, Emory University, Atlanta, Georgia, United States of America

    ยค Current address: Theoretical Biology, Utrecht University, Utrecht, Netherlands

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  • Sergei S Pilyugin,

    Affiliation: Department of Mathematics, University of Florida, Gainesville Florida, United States of America

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  • Rafi Ahmed,

    Affiliation: Emory Vaccine Center, Emory University, Atlanta, Georgia, United States of America

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  • Rustom Antia equal contributor mail

    equal contributor Contributed equally to this work with: Vitaly V Ganusov, Rustom Antia

    To whom correspondence should be addressed. E-mail: rantia@emory.edu

    Affiliation: Department of Biology, Emory University, Atlanta, Georgia, United States of America

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  • Published: June 09, 2006
  • DOI: 10.1371/journal.pcbi.0020055

About the Authors

Vitaly V Ganusov, Rustom Antia
Department of Biology, Emory University, Atlanta, Georgia, United States of America
Sergei S Pilyugin
Department of Mathematics, University of Florida, Gainesville Florida, United States of America
Rafi Ahmed
Emory Vaccine Center, Emory University, Atlanta, Georgia, United States of America

Corresponding Author

Email: rantia@emory.edu

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

R. Antia and V. V. Ganusov conceived the basic ideas. R. Ahmed helped formulate the problem and consider the implications for experimental work. R. Antia and V. V. Ganusov derived analytical approximations. V. V. Ganusov performed the simulations. V. V. Ganusov and R. Antia wrote the paper. S. S. Pilyugin contributed to the derivations and helped to modify the text.