Prioritizing Genomic Drug Targets in Pathogens: Application to Mycobacterium tuberculosis

Samiul Hasan; Sabine Daugelat; P. S. Srinivasa Rao; Mark Schreiber

doi:10.1371/journal.pcbi.0020061

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Open Access

Peer-reviewed

Research Article

Prioritizing Genomic Drug Targets in Pathogens: Application to Mycobacterium tuberculosis

Samiul Hasan,

Affiliation Novartis Institute for Tropical Diseases (NITD), Chromos, Singapore
⨯
Sabine Daugelat,

Affiliation Novartis Institute for Tropical Diseases (NITD), Chromos, Singapore
⨯
P. S. Srinivasa Rao,

Affiliation Novartis Institute for Tropical Diseases (NITD), Chromos, Singapore
⨯
Mark Schreiber

*To whom correspondence should be addressed. E-mail: mark.schreiber@novartis.com

Affiliation Novartis Institute for Tropical Diseases (NITD), Chromos, Singapore
⨯

Prioritizing Genomic Drug Targets in Pathogens: Application to Mycobacterium tuberculosis

Samiul Hasan,
Sabine Daugelat,
P. S. Srinivasa Rao,
Mark Schreiber

Published: June 9, 2006
https://doi.org/10.1371/journal.pcbi.0020061

About the Authors

Samiul Hasan

Affiliation Novartis Institute for Tropical Diseases (NITD), Chromos, Singapore

Sabine Daugelat

Affiliation Novartis Institute for Tropical Diseases (NITD), Chromos, Singapore

P. S. Srinivasa Rao

Affiliation Novartis Institute for Tropical Diseases (NITD), Chromos, Singapore

Mark Schreiber

*To whom correspondence should be addressed. E-mail: mark.schreiber@novartis.com

Affiliation Novartis Institute for Tropical Diseases (NITD), Chromos, Singapore

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

SH and MS conceived and designed the experiments. SH performed the experiments. SH, SD, PSSR, and MS analyzed the data. SH and MS contributed reagents/materials/analysis tools. SH and MS wrote the paper.

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Mycobacterium tuberculosis
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Drug discovery
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Body weight
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Tuberculosis
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Drug metabolism
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Protein domains
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Drug research and development
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Tuberculosis drug discovery
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